A Study of the Correlation between VEP and Clinical Severity in Children with Autism Spectrum Disorder

Joint Authors

Sayorwan, Winai
Phianchana, Nutthida
Permpoonputtana, Kannika
Siripornpanich, Vorasith

Source

Autism Research and Treatment

Issue

Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2018-01-14

Country of Publication

Egypt

No. of Pages

8

Main Subjects

Diseases

Abstract EN

Visual evoked potential (VEP) is a technique used to assess the brain’s electrical response to visual stimuli.

The aims of this study were to examine neural transmission within the visual pathway through VEP testing in preschool children with autism spectrum disorder (ASD) and compare it to age-matched controls, as well as search for a correlation between the VEP parameters and the symptoms of ASD.

Participants were composed of ASD children (9 males) and typically developing children (8 males and 4 females), aged between 3 and 5 years.

Checkerboards were chosen as the pattern-reversal VEP.

The clinical severity of ASD was assessed using the Autism Treatment Evaluation Checklist (ATEC) and the Vineland Adaptive Behavior Scales 2nd edition (VABS-II).

Our findings demonstrated that children with ASD had significantly longer N145 latency compared to the controls.

A longer N145 latency correlated with a higher score of ATEC within the sensory/cognitive awareness subdomain.

In addition, a slower N145 response was also associated with a lower VABS-II score within the socialization domain.

The correlation between longer VEP latency and abnormal behaviors in children with ASD suggests a delayed neural communication within other neural circuits, apart from the visual pathway.

These lines of evidence support the possibility of using VEP, along with clinical parameters, for the assessment of ASD severity.

American Psychological Association (APA)

Sayorwan, Winai& Phianchana, Nutthida& Permpoonputtana, Kannika& Siripornpanich, Vorasith. 2018. A Study of the Correlation between VEP and Clinical Severity in Children with Autism Spectrum Disorder. Autism Research and Treatment،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1123040

Modern Language Association (MLA)

Sayorwan, Winai…[et al.]. A Study of the Correlation between VEP and Clinical Severity in Children with Autism Spectrum Disorder. Autism Research and Treatment No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1123040

American Medical Association (AMA)

Sayorwan, Winai& Phianchana, Nutthida& Permpoonputtana, Kannika& Siripornpanich, Vorasith. A Study of the Correlation between VEP and Clinical Severity in Children with Autism Spectrum Disorder. Autism Research and Treatment. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1123040

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1123040