Synthesis and Characterization of Oxidovanadium(IV) Complexes of 2-((E)-(6-Fluorobenzo[d]thiazol-2-ylimino)methyl)-6-methoxyphenol and Their Antimicrobial, Antioxidant, and DNA-Binding Studies
Joint Authors
Revanasiddappa, Hosakere Doddarevanna
Savithri, K.
Source
Bioinorganic Chemistry and Applications
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-06-27
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Two novel oxidovanadium(IV) complexes with a new bidentate (O- and N-) imine-based ligand 2-((E)-(6-fluorobenzo[d]thiazol-2-ylimino)methyl)-6-methoxyphenol (HL) were synthesized under in situ experimental condition where VOSO4 acts as a kinetic template in the ratio 2 : 1 (L : M) and mixed ligand complex using 1,10-phenanthroline (phen) in 1 : 1 : 1 (L : M : phen) ratio.
The synthesized compounds were structurally characterized by microanalysis, magnetic susceptibility, FTIR, electronic spectra, TG/DTA, ESR, and molar conductance studies.
Based on the spectral studies, the complexes have the general composition [VO(L)2] (C1) and [VO(L)phen] (C2) in a square pyramid geometrical fashion.
The synthesized compounds were primarily screened for their in vitro growth inhibiting activity against different strains of bacteria, namely, E.
coli, B.
subtilis, S.
aureus, and P.
aeruginosa by the disc diffusion method.
Also, the antifungal activity was determined against C.
albicans and A.
niger by the Bateman poisoned technique.
The in vitro antioxidant activity of all the compounds was determined by DPPH free radical-scavenging assay.
Intercalative mode of DNA-binding properties of the oxidovanadium(IV) complexes with calf-thymus DNA (CT-DNA) was investigated using UV, fluorescence spectra, and viscosity measurements.
American Psychological Association (APA)
Savithri, K.& Revanasiddappa, Hosakere Doddarevanna. 2018. Synthesis and Characterization of Oxidovanadium(IV) Complexes of 2-((E)-(6-Fluorobenzo[d]thiazol-2-ylimino)methyl)-6-methoxyphenol and Their Antimicrobial, Antioxidant, and DNA-Binding Studies. Bioinorganic Chemistry and Applications،Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1123100
Modern Language Association (MLA)
Savithri, K.& Revanasiddappa, Hosakere Doddarevanna. Synthesis and Characterization of Oxidovanadium(IV) Complexes of 2-((E)-(6-Fluorobenzo[d]thiazol-2-ylimino)methyl)-6-methoxyphenol and Their Antimicrobial, Antioxidant, and DNA-Binding Studies. Bioinorganic Chemistry and Applications No. 2018 (2018), pp.1-12.
https://search.emarefa.net/detail/BIM-1123100
American Medical Association (AMA)
Savithri, K.& Revanasiddappa, Hosakere Doddarevanna. Synthesis and Characterization of Oxidovanadium(IV) Complexes of 2-((E)-(6-Fluorobenzo[d]thiazol-2-ylimino)methyl)-6-methoxyphenol and Their Antimicrobial, Antioxidant, and DNA-Binding Studies. Bioinorganic Chemistry and Applications. 2018. Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1123100
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1123100