![](/images/graphics-bg.png)
An Overview of Molecular Mechanism, Clinicopathological Factors, and Treatment in NUT Carcinoma
Joint Authors
Huang, Qian W.
He, Li J.
Zheng, Shuang
Liu, Tao
Peng, Bei N.
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-11-11
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
NUT carcinoma (NC) is a rare and poorly differentiated tumor, with highly aggressive and fatal neoplasm.
NC is characterized by chromosomal rearrangement involving NUTM1 gene, but lack of specific clinical and histomorphological features.
It is more common in midline anatomic sites, such as head and neck, mediastinum, and other midline organs.
NC may occur at any age, but mainly in children and young adults.
In addition, male and female are equally affected.
Most clinicians lack a clear understanding of the disease, and NC diagnostic reagents are still not widely used; therefore, misdiagnosis often occurs in clinic.
Due to the highly aggressive nature of the disease and the insensitivity to nonspecific chemotherapy or radiotherapy, many patients have died before the confirmation of NC.
In fact, the true incidence of NC is much higher than the current statistics.
In recent years, targeted therapy for NC has also made some progress.
This article aims to summarize the molecular mechanisms, clinicopathological characteristics, and treatment of NC.
American Psychological Association (APA)
Huang, Qian W.& He, Li J.& Zheng, Shuang& Liu, Tao& Peng, Bei N.. 2019. An Overview of Molecular Mechanism, Clinicopathological Factors, and Treatment in NUT Carcinoma. BioMed Research International،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1123109
Modern Language Association (MLA)
Huang, Qian W.…[et al.]. An Overview of Molecular Mechanism, Clinicopathological Factors, and Treatment in NUT Carcinoma. BioMed Research International No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1123109
American Medical Association (AMA)
Huang, Qian W.& He, Li J.& Zheng, Shuang& Liu, Tao& Peng, Bei N.. An Overview of Molecular Mechanism, Clinicopathological Factors, and Treatment in NUT Carcinoma. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1123109
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1123109