Determination of Length of Interdigitation Zone by Optical Coherence Tomography and Retinal Sensitivity by Microperimetry and Their Relationship to Progression of Retinitis Pigmentosa
Joint Authors
Miura, Gen
Baba, Takayuki
Chiba, Akihiro
Yamamoto, Shuichi
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-06-20
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Purpose.
To investigate the annual progression of retinitis pigmentosa (RP) by changes in retinal sensitivity and length of photoreceptor microstructures.
Method.
The medical records of patients with typical RP followed at Chiba University Hospital were reviewed.
The retinal sensitivity was measured by Micro Perimeter-1, and the lengths of the intact external limiting membrane (ELM), ellipsoid zone (EZ), and interdigitation zone (IZ) were measured by spectral-domain optical coherence tomography.
The baseline values and annual progression rates were determined.
The significance of the correlations among these factors was determined by generalized estimating equation regression analysis.
Results.
Forty-six eyes of 24 patients who were examined over a mean follow-up period of 3 years were studied.
The annual changes in the retinal sensitivity (p = 0.0035) and the lengths of the EZ (p = 0.037) and IZ (p = 0.0033) were significantly correlated with their baseline values.
The annual change in the retinal sensitivity was significantly correlated with the length of the EZ at the baseline (p = 0.020).
Conclusions.
The significant correlation between the annual progression of the retinal sensitivity and the baseline retinal sensitivity and lengths of the EZ and IZ in patients with RP indicate that the retinal sensitivity, the EZ, and the IZ can be useful parameters to predict the annual progression of RP.
American Psychological Association (APA)
Chiba, Akihiro& Miura, Gen& Baba, Takayuki& Yamamoto, Shuichi. 2019. Determination of Length of Interdigitation Zone by Optical Coherence Tomography and Retinal Sensitivity by Microperimetry and Their Relationship to Progression of Retinitis Pigmentosa. BioMed Research International،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1123193
Modern Language Association (MLA)
Chiba, Akihiro…[et al.]. Determination of Length of Interdigitation Zone by Optical Coherence Tomography and Retinal Sensitivity by Microperimetry and Their Relationship to Progression of Retinitis Pigmentosa. BioMed Research International No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1123193
American Medical Association (AMA)
Chiba, Akihiro& Miura, Gen& Baba, Takayuki& Yamamoto, Shuichi. Determination of Length of Interdigitation Zone by Optical Coherence Tomography and Retinal Sensitivity by Microperimetry and Their Relationship to Progression of Retinitis Pigmentosa. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1123193
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1123193