Research Progress on the Animal Models of Drug-Induced Liver Injury: Current Status and Further Perspectives
Joint Authors
Pan, Yingying
Cao, Mingzhu
You, Danming
Qin, Genggeng
Liu, Zhi
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-04-15
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Drug-induced liver injury (DILI) is a major concern in clinical studies as well as in postmarketing surveillance.
It is necessary to establish an animal model of DILI for thorough investigation of mechanisms of DILI and searching for protective medications.
This article reviews the current status and future perspective on establishment of DILI models based on different hepatotoxic drugs, as well as the underlying mechanisms of liver function damage induced by specific medicine.
Therefore, information from this article can help researchers make a suitable selection of animal models for further study.
American Psychological Association (APA)
Pan, Yingying& Cao, Mingzhu& You, Danming& Qin, Genggeng& Liu, Zhi. 2019. Research Progress on the Animal Models of Drug-Induced Liver Injury: Current Status and Further Perspectives. BioMed Research International،Vol. 2019, no. 2019, pp.1-12.
https://search.emarefa.net/detail/BIM-1123253
Modern Language Association (MLA)
Pan, Yingying…[et al.]. Research Progress on the Animal Models of Drug-Induced Liver Injury: Current Status and Further Perspectives. BioMed Research International No. 2019 (2019), pp.1-12.
https://search.emarefa.net/detail/BIM-1123253
American Medical Association (AMA)
Pan, Yingying& Cao, Mingzhu& You, Danming& Qin, Genggeng& Liu, Zhi. Research Progress on the Animal Models of Drug-Induced Liver Injury: Current Status and Further Perspectives. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-12.
https://search.emarefa.net/detail/BIM-1123253
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1123253
