![](/images/graphics-bg.png)
Modulated Autophagy by MicroRNAs in Osteoarthritis Chondrocytes
Joint Authors
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-05-08
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Osteoarthritis (OA) is a chronic joint disease characterized by articular cartilage regression.
The etiology of OA is diverse, the exact pathogenesis of which remains unclear.
Autophagy is a conserved maintenance mechanism in eukaryotic cells.
Dysfunction of chondrocyte autophagy is regarded as a crucial pathogenesis of cartilage degradation in OA.
MircoRNAs (miRNAs) are a category of small noncoding RNAs, acting as posttranscriptional modulators that regulate biological processes and cell signaling pathways via target genes.
A series of miRNAs are involved in the progression of chondrocyte autophagy and are connected with numerous factors and pathways.
This article focuses on the mechanisms of chondrocyte autophagy in OA and reviews the role of miRNA in their modulation.
Potentially relevant miRNAs are also discussed in order to provide new directions for future research and improve our understanding of the autophagic network of miRNAs.
American Psychological Association (APA)
Yu, Yinghao& Zhao, Jijun. 2019. Modulated Autophagy by MicroRNAs in Osteoarthritis Chondrocytes. BioMed Research International،Vol. 2019, no. 2019, pp.1-14.
https://search.emarefa.net/detail/BIM-1123388
Modern Language Association (MLA)
Yu, Yinghao& Zhao, Jijun. Modulated Autophagy by MicroRNAs in Osteoarthritis Chondrocytes. BioMed Research International No. 2019 (2019), pp.1-14.
https://search.emarefa.net/detail/BIM-1123388
American Medical Association (AMA)
Yu, Yinghao& Zhao, Jijun. Modulated Autophagy by MicroRNAs in Osteoarthritis Chondrocytes. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-14.
https://search.emarefa.net/detail/BIM-1123388
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1123388