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Unveiling the Role of DNA Methylation in Kidney Transplantation: Novel Perspectives toward Biomarker Identification
Joint Authors
Veroux, Massimiliano
Maugeri, Andrea
Basile, Guido
Zamboni, Matilde
Bernardini, Giulia
Barchitta, Martina
Agodi, Antonella
Corona, Daniela
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-01-15
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The burden of chronic kidney disease is dramatically rising, making it a major public health concern worldwide.
Kidney transplantation is now the best treatment for patients with end-stage renal disease.
Although kidney transplantation may improve survival and quality of life, its long-term results are hampered by immune- and/or non-immune-mediated complications.
Thus, the identification of transplanted patients with a higher risk of posttransplant complications has become a big challenge for public health.
However, current biomarkers of posttransplant complications have a poor predictive value, rising the need to explore novel approaches for the management of transplant patient.
In this review we summarize the emerging literature about DNA methylation in kidney transplant complications, in order to highlight its perspectives toward biomarker identification.
In the forthcoming future the monitoring of DNA methylation in kidney transplant patients could become a plausible strategy toward the prevention and/or treatment of kidney transplant complications.
American Psychological Association (APA)
Agodi, Antonella& Barchitta, Martina& Maugeri, Andrea& Basile, Guido& Zamboni, Matilde& Bernardini, Giulia…[et al.]. 2019. Unveiling the Role of DNA Methylation in Kidney Transplantation: Novel Perspectives toward Biomarker Identification. BioMed Research International،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1123425
Modern Language Association (MLA)
Agodi, Antonella…[et al.]. Unveiling the Role of DNA Methylation in Kidney Transplantation: Novel Perspectives toward Biomarker Identification. BioMed Research International No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1123425
American Medical Association (AMA)
Agodi, Antonella& Barchitta, Martina& Maugeri, Andrea& Basile, Guido& Zamboni, Matilde& Bernardini, Giulia…[et al.]. Unveiling the Role of DNA Methylation in Kidney Transplantation: Novel Perspectives toward Biomarker Identification. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1123425
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1123425