Multimodality Treatment Options and Outcomes of Laryngeal Carcinosarcoma: A Clinical Analysis of a Rare Tumor from a Single Hospital
Joint Authors
Li, Guojun
Zhang, Yang
Huang, Zhigang
Gross, Neil
Fang, Jugao
Chen, Xiaohong
Chen, Xuejun
Hou, Lizhen
Li, Pingdong
Zhong, Qi
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-06-16
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Primary laryngeal carcinosarcoma is a rare type of malignancies, and the standard therapeutic protocol for its treatment has yet to be established.
This retrospective study analyzed the clinical and pathological characteristics, risk factors, treatment options, and prognosis of 13 patients with primary laryngeal carcinosarcomas.
This case series included 11 males and 2 females with an age range from 32 to 78 years at diagnosis.
The initial clinical symptoms included hoarseness, dyspnea, and foreign body sensation in the throat.
The primary tumor sites were at the glottis, supraglottis, and larynx.
All these patients were active or passive smokers, and more than half of them were alcohol addictive.
The surgical treatment for laryngeal carcinosarcomas included CO2 laser surgery in seven cases, partial laryngectomy and neck dissection in three cases, and total laryngectomy and neck dissection in three cases.
Among them, seven cases received postoperative radiotherapy.
After follow-up with a mean of 31.15-month, four cases died.
Primary laryngeal carcinosarcoma is a rare but more aggressive malignancy.
Contralateral lymph node metastasis can occur at the early stage of this disease.
A treatment combining surgery and postoperative radiotherapy is strongly recommended.
American Psychological Association (APA)
Zhang, Yang& Huang, Zhigang& Gross, Neil& Fang, Jugao& Chen, Xiaohong& Chen, Xuejun…[et al.]. 2019. Multimodality Treatment Options and Outcomes of Laryngeal Carcinosarcoma: A Clinical Analysis of a Rare Tumor from a Single Hospital. BioMed Research International،Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1123489
Modern Language Association (MLA)
Zhang, Yang…[et al.]. Multimodality Treatment Options and Outcomes of Laryngeal Carcinosarcoma: A Clinical Analysis of a Rare Tumor from a Single Hospital. BioMed Research International No. 2019 (2019), pp.1-4.
https://search.emarefa.net/detail/BIM-1123489
American Medical Association (AMA)
Zhang, Yang& Huang, Zhigang& Gross, Neil& Fang, Jugao& Chen, Xiaohong& Chen, Xuejun…[et al.]. Multimodality Treatment Options and Outcomes of Laryngeal Carcinosarcoma: A Clinical Analysis of a Rare Tumor from a Single Hospital. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1123489
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1123489