Whether Keratectasia Area Shown in Corneal Topography Is Appropriate for Evaluating the Effect of Corneal Cross-Linking for Keratoconus: A 12-Month Follow-Up Study
Joint Authors
Mu, Guo-ying
Wang, Jia
Li, Zhiwei
Zhang, Huankai
Gao, Ning
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-04-03
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Purpose.
To analyze the keratectasia area (KEA) shown in corneal topography before and after corneal cross-linking (CXL) in patients with progressive keratoconus (KC) and figure out whether KEA is appropriate for evaluating the effect of CXL.
Methods.
A retrospective analysis was conducted in 34 eyes from 24 progressive KC patients who have underwent CXL from 2015 to 2017.
Area with K-value more than 47D shown in the corneal topography was marked and identified as KEA.
Keratometry (K1, K2, and Kmax), KEA, thinnest corneal thickness (TCT), and endothelial cell density (ECD) were evaluated preoperatively or at months 3, 6, and 12 postoperatively.
The changes of KEA before and after operation were evaluated.
The relation of KEA and other parameters, including Kmax and TCT, was analyzed.
Results.
Linear regression model revealed the KEA, Kmax, K1, and K2 decreased after CXL in model y = 0.9622 -0.02408 x (P<0.05), y = 0.9982 -0.003469 x(P<0.05), y = 0.9977 + -0.001347 x(P<0.05), y = 0.9992 + -0.001779 x(P<0.05) (y represents KEA, Kmax, K1, or K2; x represents time (month)).
The KEA is significantly decreased in early stage (before month 3) (P<0.05); however, the Kmax, K1, and K2 have no significant decrease in early stage (P= 0.09, 0.19, 0.32).
Conclusions.
The KEA is more sensitive than K-value in describing the morphological changes of cornea after CXL, especially in early stage after treatment.
American Psychological Association (APA)
Wang, Jia& Li, Zhiwei& Zhang, Huankai& Gao, Ning& Mu, Guo-ying. 2019. Whether Keratectasia Area Shown in Corneal Topography Is Appropriate for Evaluating the Effect of Corneal Cross-Linking for Keratoconus: A 12-Month Follow-Up Study. BioMed Research International،Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1123498
Modern Language Association (MLA)
Wang, Jia…[et al.]. Whether Keratectasia Area Shown in Corneal Topography Is Appropriate for Evaluating the Effect of Corneal Cross-Linking for Keratoconus: A 12-Month Follow-Up Study. BioMed Research International No. 2019 (2019), pp.1-5.
https://search.emarefa.net/detail/BIM-1123498
American Medical Association (AMA)
Wang, Jia& Li, Zhiwei& Zhang, Huankai& Gao, Ning& Mu, Guo-ying. Whether Keratectasia Area Shown in Corneal Topography Is Appropriate for Evaluating the Effect of Corneal Cross-Linking for Keratoconus: A 12-Month Follow-Up Study. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1123498
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1123498