Insights on the Multifunctional Activities of Magnolol
Joint Authors
Zhang, Jianhong
Wu, Longhuo
Shi, Weimei
Chen, Zhixi
Huang, Xianhua
Chen, Meiling
Zhang, Rui
Huang, Hao
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-05-23
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Over years, various biological constituents are isolated from Traditional Chinese Medicine and confirmed to show multifunctional activities.
Magnolol, a hydroxylated biphenyl natural compound isolated from Magnolia officinalis, has been extensively documented and shows a range of biological activities.
Many signaling pathways include, but are not limited to, NF-κB/MAPK, Nrf2/HO-1, and PI3K/Akt pathways, which are implicated in the biological functions mediated by magnolol.
Thus, magnolol is considered as a promising therapeutic agent for clinic research.
However, the low water solubility, the low bioavailability, and the rapid metabolism of magnolol dramatically limit its clinical application.
In this review, we will comprehensively discuss the last five-year progress of the biological activities of magnolol, including anti-inflammatory, antimicroorganism, antioxidative, anticancer, neuroprotective, cardiovascular protection, metabolism regulation, and ion-mediating activity.
American Psychological Association (APA)
Zhang, Jianhong& Chen, Zhixi& Huang, Xianhua& Shi, Weimei& Zhang, Rui& Chen, Meiling…[et al.]. 2019. Insights on the Multifunctional Activities of Magnolol. BioMed Research International،Vol. 2019, no. 2019, pp.1-15.
https://search.emarefa.net/detail/BIM-1123533
Modern Language Association (MLA)
Zhang, Jianhong…[et al.]. Insights on the Multifunctional Activities of Magnolol. BioMed Research International No. 2019 (2019), pp.1-15.
https://search.emarefa.net/detail/BIM-1123533
American Medical Association (AMA)
Zhang, Jianhong& Chen, Zhixi& Huang, Xianhua& Shi, Weimei& Zhang, Rui& Chen, Meiling…[et al.]. Insights on the Multifunctional Activities of Magnolol. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-15.
https://search.emarefa.net/detail/BIM-1123533
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1123533