Quorum Sensing: A Prospective Therapeutic Target for Bacterial Diseases
Joint Authors
Yin, Yulong
Jiang, Qian
Chen, Jiashun
Yang, Chengbo
Yao, Kang
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-04-04
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Bacterial quorum sensing (QS) is a cell-to-cell communication in which specific signals are activated to coordinate pathogenic behaviors and help bacteria acclimatize to the disadvantages.
The QS signals in the bacteria mainly consist of acyl-homoserine lactone, autoinducing peptide, and autoinducer-2.
QS signaling activation and biofilm formation lead to the antimicrobial resistance of the pathogens, thus increasing the therapy difficulty of bacterial diseases.
Anti-QS agents can abolish the QS signaling and prevent the biofilm formation, therefore reducing bacterial virulence without causing drug-resistant to the pathogens, suggesting that anti-QS agents are potential alternatives for antibiotics.
This review focuses on the anti-QS agents and their mediated signals in the pathogens and conveys the potential of QS targeted therapy for bacterial diseases.
American Psychological Association (APA)
Jiang, Qian& Chen, Jiashun& Yang, Chengbo& Yin, Yulong& Yao, Kang. 2019. Quorum Sensing: A Prospective Therapeutic Target for Bacterial Diseases. BioMed Research International،Vol. 2019, no. 2019, pp.1-15.
https://search.emarefa.net/detail/BIM-1123608
Modern Language Association (MLA)
Jiang, Qian…[et al.]. Quorum Sensing: A Prospective Therapeutic Target for Bacterial Diseases. BioMed Research International No. 2019 (2019), pp.1-15.
https://search.emarefa.net/detail/BIM-1123608
American Medical Association (AMA)
Jiang, Qian& Chen, Jiashun& Yang, Chengbo& Yin, Yulong& Yao, Kang. Quorum Sensing: A Prospective Therapeutic Target for Bacterial Diseases. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-15.
https://search.emarefa.net/detail/BIM-1123608
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1123608