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The Prominent Role of HMGA Proteins in the Early Management of Gastrointestinal Cancers
Joint Authors
Meireles Da Costa, Nathalia
Ribeiro Pinto, Luis Felipe
Nasciutti, Luiz Eurico
Palumbo Jr., Antonio
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-10-13
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
GI tumors represent a heterogeneous group of neoplasms concerning their natural history and molecular alterations harbored.
Nevertheless, these tumors share very high incidence and mortality rates worldwide and patients’ poor prognosis.
Therefore, the identification of specific biomarkers could increase the development of personalized medicine, in order to improve GI cancer management.
In this sense, HMGA family members (HMGA1 and HMGA2) comprise an important group of genes involved in the genesis and progression of malignant tumors.
Additionally, it has also been reported that HMGA1 and HMGA2 display an important role in the detection and progression of GI tumors.
In this way, HMGA family members could be used as reliable biomarkers able to efficiently track not only the tumor per se but also the main risk conditions related with their development of GI cancers in the future.
Finally, it shall be a promising option to revert the current scenario, once HMGA genes and proteins could represent a convergence point in the complex landscape of GI tumors.
American Psychological Association (APA)
Meireles Da Costa, Nathalia& Ribeiro Pinto, Luis Felipe& Nasciutti, Luiz Eurico& Palumbo Jr., Antonio. 2019. The Prominent Role of HMGA Proteins in the Early Management of Gastrointestinal Cancers. BioMed Research International،Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1123646
Modern Language Association (MLA)
Meireles Da Costa, Nathalia…[et al.]. The Prominent Role of HMGA Proteins in the Early Management of Gastrointestinal Cancers. BioMed Research International No. 2019 (2019), pp.1-7.
https://search.emarefa.net/detail/BIM-1123646
American Medical Association (AMA)
Meireles Da Costa, Nathalia& Ribeiro Pinto, Luis Felipe& Nasciutti, Luiz Eurico& Palumbo Jr., Antonio. The Prominent Role of HMGA Proteins in the Early Management of Gastrointestinal Cancers. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1123646
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1123646