The Effectiveness of the Whole Body Cryotherapy Strategies: A Comparison of Different Duration and Temperature on the Antioxidative Status in the Experimental Rat Model

Abstract EN

Background.

We examined the effectiveness of the systemic cryotherapy in terms of the temperature and duration of the therapeutic series measured by oxidative stress markers in the rat animal model.

Methods.

Antioxidants in serum, plasma, liver, and erythrocytes were evaluated in two study groups following 1 min exposure to − 60°C and − 90°C, for 5 and 10 days.

Results.

Superoxide dismutase activity in the tissues was lower than in the serum.

The glutathione peroxidase was significantly higher in − 60°C than in − 90°C, in both 5 and 10 days of exposition.

The liver catalase CAT were significantly lower in − 60°C when compared to − 90°C for 5 and 10 sessions of exposure.

In all analysed tissues, the sessions of cryotherapy, – 60/5 and – 60/10, were more effective in reduction malondialdehyde than sessions of − 90/5 and − 90/10.

The highest total antioxidant capacity was observed in the − 60/5 group.

Conclusions.

Whole body cryotherapy based on temperature − 60°C may be considered as more beneficial than − 90°C for most of the oxidative stress (OS) markers measured in the selected tissues.

The temp.

− 60°C is more beneficial than − 90°C when measured by activity of Total SOD, CAT, and GPx.

The therapeutic sessions − 60/10 and − 60/5 were the optimal schemes of WBC model in terms of TAC and MDA amount.