Exosomes Modulate the Viral Replication and Host Immune Responses in HBV Infection
Joint Authors
Chen, Limin
Li, Shilin
Li, Shuang
Wu, Shaobo
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-05-28
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Although current diagnosis and treatment of hepatitis B virus (HBV) infection can maintain viral suppression, new therapies need to be invented to sustain off-treatment virologic suppression and reduce side effects.
Exosomes act as intercellular communicators to facilitate direct transfer of proteins, lipids, and nucleic acids between cells in vitro and in vivo.
Pioneering work has demonstrated that exosomal cargos changed markedly during HBV infection.
An improved understanding of the functions of exosomes during HBV infection could lead to a powerful new strategy for preventing and treating HBV.
In this review, we point out the role of exosomes in HBV infection: (1) exosomes could directly participate in HBV replication; (2) exosomes modulate immune response during HBV infections; (3) exosomal RNAs and proteins might be selected as novel biomarkers for the diagnosis of HBV infections; and (4) exosomes can also be designed as vaccines.
American Psychological Association (APA)
Li, Shuang& Li, Shilin& Wu, Shaobo& Chen, Limin. 2019. Exosomes Modulate the Viral Replication and Host Immune Responses in HBV Infection. BioMed Research International،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1123697
Modern Language Association (MLA)
Li, Shuang…[et al.]. Exosomes Modulate the Viral Replication and Host Immune Responses in HBV Infection. BioMed Research International No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1123697
American Medical Association (AMA)
Li, Shuang& Li, Shilin& Wu, Shaobo& Chen, Limin. Exosomes Modulate the Viral Replication and Host Immune Responses in HBV Infection. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1123697
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1123697