Medical Cannabinoids for Cancer Cachexia: A Systematic Review and Meta-Analysis
Joint Authors
Wang, Jing
Wang, Yanling
Tong, Mengting
Pan, Hongming
Li, Da
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-06-23
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objectives.
Cancer cachexia (CCA) is an intractable and ineffective metabolic syndrome that attacks 50–80% of cancer patients.
It reduces patient’s life quality, affects the efficacy of treatment, and then increases their mortality; however, there are no established therapeutic strategies for CCA in the world.
In this study, we assess the positive and negative effects of cannabinoid in the treatment of CCA.
Methods.
We searched the Cochrane Central Register of Controlled Trials (CENTRAL) in The Cochrane Library, MEDLINE, EMBASE, Web of Science, and PubMed up to December 2017.
Results.
Of the 256 screened studies, three studies with a total of 592 participants were included.
Compared with placebo, cannabinoid increased the appetite (MD 0.27, 95% CI -0.51 to 1.04; n= 3) but failed to improve the overall quality of life (QOL; MD -12.39, 95% CI [-24.21 to -0.57; n = 2), and a total of 441 patients had 607 adverse events (AEs; 496 in the cannabinoid group and 111 in the placebo group).
Conclusions.
Our analysis showed cannabinoid is effective in increasing appetite in cancer patients.
However, it declines the quality of life, which may be due to the side effects of cannabinoid.
American Psychological Association (APA)
Wang, Jing& Wang, Yanling& Tong, Mengting& Pan, Hongming& Li, Da. 2019. Medical Cannabinoids for Cancer Cachexia: A Systematic Review and Meta-Analysis. BioMed Research International،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1124131
Modern Language Association (MLA)
Wang, Jing…[et al.]. Medical Cannabinoids for Cancer Cachexia: A Systematic Review and Meta-Analysis. BioMed Research International No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1124131
American Medical Association (AMA)
Wang, Jing& Wang, Yanling& Tong, Mengting& Pan, Hongming& Li, Da. Medical Cannabinoids for Cancer Cachexia: A Systematic Review and Meta-Analysis. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1124131
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1124131