Bacterial Extracellular DNA Production Is Associated with Outcome of Prosthetic Joint Infections
Joint Authors
Zatorska, Beata
Haffner, Nicolas
Segagni Lusignani, Luigi
Presterl, Elisabeth
Diab-Elschahawi, Magda
Arciola, Carla Renata
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-10-22
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
In a retrospective study the association of the production of extracellular DNA (eDNA) in biofilms of clinical staphylococcal isolates from 60 patients with prosthetic joint infection (PJI) and the clinical outcome were investigated.
Data from a previous study on eDNA production determined in 24-hour biofilms of staphylococcal isolates (Staphylococcus aureus n=30, Staphylococcus epidermidis n=30) was correlated with the patients’ clinical outcome after 3 and 12 months.
Statistical analysis was performed using either the Spearman’s rank correlations test or the t-test.
eDNA production of S.
epidermidis in 24-hour biofilms correlated with the patients’ outcome ‘not cured‘ after 12 months.
For S.
aureus no such correlation was detected.
Thus, eDNA may be a virulence factor of S.
epidermidis.
Quantification of eDNA production as a surrogate marker for biofilm formation might be a potential predictive marker for the management of PJI.
American Psychological Association (APA)
Zatorska, Beata& Arciola, Carla Renata& Haffner, Nicolas& Segagni Lusignani, Luigi& Presterl, Elisabeth& Diab-Elschahawi, Magda. 2018. Bacterial Extracellular DNA Production Is Associated with Outcome of Prosthetic Joint Infections. BioMed Research International،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1124135
Modern Language Association (MLA)
Zatorska, Beata…[et al.]. Bacterial Extracellular DNA Production Is Associated with Outcome of Prosthetic Joint Infections. BioMed Research International No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1124135
American Medical Association (AMA)
Zatorska, Beata& Arciola, Carla Renata& Haffner, Nicolas& Segagni Lusignani, Luigi& Presterl, Elisabeth& Diab-Elschahawi, Magda. Bacterial Extracellular DNA Production Is Associated with Outcome of Prosthetic Joint Infections. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1124135
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1124135