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Infant Skin Barrier, Structure, and Enzymatic Activity Differ from Those of Adult in an East Asian Cohort
Joint Authors
Liu, Qiwei
Zhang, Yanhui
Danby, Simon G.
Cork, Michael J.
Stamatas, Georgios N.
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-07-12
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Skin physiology is dynamically changing over the first years of postnatal life; however, ethnic variations are still unclear.
The aim of this study was to characterize infant skin barrier function, epidermal structure, and desquamation-related enzymatic activity as compared to that of adult skin in an East Asian population.
The skin properties of 52 infants (3-24 months) and 27 adults (20-40 years) were assessed by noninvasive methods at the dorsal forearm and upper inner arm.
Transepidermal water loss and skin surface conductance values were higher and more dispersed for infants compared to adults.
Infant skin surface pH was slightly lower than adult on the dorsal forearm.
The infant SC and viable epidermis were thinner compared to adults with differences that were site-specific.
Although the chymotrypsin-like activity for infant skin was comparable to adult level, the caseinolytic specific activity was significantly higher for the infant cohort.
These observations indicate a differently controlled pattern of corneocyte desquamation in infants.
In conclusion, structural and functional differences exist between infant and adult skin in the East Asian population pointing to dynamic maturation of the epidermal barrier early in life.
American Psychological Association (APA)
Liu, Qiwei& Zhang, Yanhui& Danby, Simon G.& Cork, Michael J.& Stamatas, Georgios N.. 2018. Infant Skin Barrier, Structure, and Enzymatic Activity Differ from Those of Adult in an East Asian Cohort. BioMed Research International،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1124232
Modern Language Association (MLA)
Liu, Qiwei…[et al.]. Infant Skin Barrier, Structure, and Enzymatic Activity Differ from Those of Adult in an East Asian Cohort. BioMed Research International No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1124232
American Medical Association (AMA)
Liu, Qiwei& Zhang, Yanhui& Danby, Simon G.& Cork, Michael J.& Stamatas, Georgios N.. Infant Skin Barrier, Structure, and Enzymatic Activity Differ from Those of Adult in an East Asian Cohort. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1124232
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1124232