EIT Imaging of Intracranial Hemorrhage in Rabbit Models Is Influenced by the Intactness of Cranium
Joint Authors
Xu, Canhua
Dai, Meng
Shi, Xuetao
Dong, Xiuzhen
Fu, Feng
Liu, Xue-Chao
Li, Hao-Ting
Yang, Bin
Wang, Hang
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-11-19
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Electrical impedance tomography (EIT) has been shown to be a promising, bedside imaging method to monitor the progression of intracranial hemorrhage (ICH).
However, the observed impedance changes within brain related to ICH differed among groups, and we hypothesized that the cranium intactness (open or closed) may be the one of potential reasons leading to the difference.
Therefore, the aim of this study was to investigate this effect of open or closed cranium on impedance changes within brain in the rabbit ICH model.
In this study, we first established the ICH model in 12 rabbits with the open cranium and in 12 rabbits with the closed cranium.
Simultaneously, EIT measurements on the rabbits’ heads were performed to record the impedance changes caused by injecting the autologous nonheparinized blood into cerebral parenchyma.
Finally, the regional impedance changes on EIT images and the whole impedance changes were analyzed.
It was surprisingly found that when the cranium was open, the impedance of the area where the blood was injected, as well as the whole brain impedance, decreased with the amount of blood being injected; when the cranium was closed, while the impedance of the area where blood was not injected continued to increase, the impedance of the area where blood was injected decreased within 20s of the blood being injected and then remained almost unchanged, and the whole brain impedance had a small fall and then notably increased.
The results have validated that the cranium completeness (open or closed) has influences on impedance changes within brain when using EIT to monitor ICH.
In future study on application of EIT to monitor ICH, the cranium completeness should be taken into account for establishing an ICH model and analyzing the corresponding EIT results.
American Psychological Association (APA)
Dai, Meng& Liu, Xue-Chao& Li, Hao-Ting& Xu, Canhua& Yang, Bin& Wang, Hang…[et al.]. 2018. EIT Imaging of Intracranial Hemorrhage in Rabbit Models Is Influenced by the Intactness of Cranium. BioMed Research International،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1124245
Modern Language Association (MLA)
Dai, Meng…[et al.]. EIT Imaging of Intracranial Hemorrhage in Rabbit Models Is Influenced by the Intactness of Cranium. BioMed Research International No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1124245
American Medical Association (AMA)
Dai, Meng& Liu, Xue-Chao& Li, Hao-Ting& Xu, Canhua& Yang, Bin& Wang, Hang…[et al.]. EIT Imaging of Intracranial Hemorrhage in Rabbit Models Is Influenced by the Intactness of Cranium. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1124245
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1124245