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Mechanical Properties and Biological Behavior of 3D Matrices Produced by Electrospinning from Protein-Enriched Polyurethane
Joint Authors
Pokushalov, Evgeny A.
Chernonosova, Vera S.
Gostev, Alexander A.
Gao, Yun
Chesalov, Yuriy A.
Shutov, Alexey V.
Karpenko, Andrey A.
Laktionov, Pavel P.
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-06-26
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Properties of matrices manufactured by electrospinning from solutions of polyurethane Tecoflex EG-80A with gelatin in 1,1,1,3,3,3-hexafluoroisopropanol were studied.
The concentration of gelatin added to the electrospinning solution was shown to influence the mechanical properties of matrices: the dependence of matrix tensile strength on protein concentration is described by a bell-shaped curve and an increase in gelatin concentration added to the elasticity of the samples.
SEM, FTIR spectroscopy, and mechanical testing demonstrate that incubation of matrices in phosphate buffer changes the structure of the fibers and alters the polyurethane-gelatin interactions, increasing matrix durability.
The ability of the matrices to maintain adhesion and proliferation of human endothelial cells was studied.
The results suggest that matrices made of 3% polyurethane solution with 15% gelatin (wt/wt) and treated with glutaraldehyde are the optimal variant for cultivation of endothelial cells.
American Psychological Association (APA)
Chernonosova, Vera S.& Gostev, Alexander A.& Gao, Yun& Chesalov, Yuriy A.& Shutov, Alexey V.& Pokushalov, Evgeny A.…[et al.]. 2018. Mechanical Properties and Biological Behavior of 3D Matrices Produced by Electrospinning from Protein-Enriched Polyurethane. BioMed Research International،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1124289
Modern Language Association (MLA)
Chernonosova, Vera S.…[et al.]. Mechanical Properties and Biological Behavior of 3D Matrices Produced by Electrospinning from Protein-Enriched Polyurethane. BioMed Research International No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1124289
American Medical Association (AMA)
Chernonosova, Vera S.& Gostev, Alexander A.& Gao, Yun& Chesalov, Yuriy A.& Shutov, Alexey V.& Pokushalov, Evgeny A.…[et al.]. Mechanical Properties and Biological Behavior of 3D Matrices Produced by Electrospinning from Protein-Enriched Polyurethane. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1124289
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1124289