Gender Differences in Cardiovascular Risk Profile in Rheumatoid Arthritis Patients with Low Disease Activity
Joint Authors
Majdan, Maria
Targońska-Stępniak, Bożena
Biskup, Małgorzata
Biskup, Wojciech
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-03-28
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Objective.
Patients with rheumatoid arthritis (RA) have an excess risk of cardiovascular (CV) disease (CVD).
The objective of the study was to compare CV risk profile in female and male RA patients with low disease activity.
Materials and Methods.
The study group consisted of 70 RA patients with continuous low disease activity and no CVD (54 women, 16 men) and 33 healthy controls of comparable age.
The groups were assessed for blood pressure, serum amino-terminal pro-brain natriuretic peptide (NT-proBNP), carotid intima media thickness (cIMT), electrocardiography, ejection fraction (EF), and diastolic dysfunction (DD).
Results.
Significantly higher burden of atherosclerosis, as revealed by higher cIMT, was found in males [0.93 (0.2) mm] vs females [0.80 (0.2) mm].
The risk of 10-year CVD was significantly higher in men than in women with RA.
High/very high risk of fatal CVD was found in 62.5% of male patients.
Males were significantly more often current/ex-smokers and had lower HDL-cholesterol and higher atherogenic index.
There were no significant differences in NT-proBNP, QTc duration, and parameters of EF and DD.
Conclusions.
In RA patients with continued low disease activity, a higher burden of atherosclerosis was found in males than in females.
The data suggest a significant impact of traditional CV risk factors.
American Psychological Association (APA)
Targońska-Stępniak, Bożena& Biskup, Małgorzata& Biskup, Wojciech& Majdan, Maria. 2019. Gender Differences in Cardiovascular Risk Profile in Rheumatoid Arthritis Patients with Low Disease Activity. BioMed Research International،Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1124517
Modern Language Association (MLA)
Targońska-Stępniak, Bożena…[et al.]. Gender Differences in Cardiovascular Risk Profile in Rheumatoid Arthritis Patients with Low Disease Activity. BioMed Research International No. 2019 (2019), pp.1-7.
https://search.emarefa.net/detail/BIM-1124517
American Medical Association (AMA)
Targońska-Stępniak, Bożena& Biskup, Małgorzata& Biskup, Wojciech& Majdan, Maria. Gender Differences in Cardiovascular Risk Profile in Rheumatoid Arthritis Patients with Low Disease Activity. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1124517
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1124517