Extra Dose of Vitamin C Based on a Daily Supplementation Shortens the Common Cold: A Meta-Analysis of 9 Randomized Controlled Trials
Joint Authors
Bu, Huaien
Zhao, Wenli
Ran, Li
Wang, Jingxia
Zhao, Ye
Tseng, Yiider
Wang, Hongwu
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-07-05
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Aim.
To investigate whether vitamin C is effective in the treatment of the common cold.
Method.
After systematically searching the National Library of Medicine (PubMed), Cochrane Library, Elsevier, China National Knowledge Infrastructure (CNKI), VIP databases, and WANFANG databases, 9 randomized placebo-controlled trials were included in our meta-analysis in RevMan 5.3 software, all of which were in English.
Results.
In the evaluation of vitamin C, administration of extra therapeutic doses at the onset of cold despite routine supplementation was found to help reduce its duration (mean difference (MD) = -0.56, 95% confidence interval (CI) [-1.03, -0.10], and P = 0.02), shorten the time of confinement indoors (MD = -0.41, 95% CI [-0.62, -0.19], and P = 0.0002), and relieve the symptoms associated with it, including chest pain (MD = -0.40, 95% CI [-0.77, -0.03], and P = 0.03), fever (MD = -0.45, 95% CI [-0.78, -0.11], and P = 0.009), and chills (MD = -0.36, 95% CI [-0.65, -0.07], and P = 0.01).
Conclusions.
Extra doses of vitamin C could benefit some patients who contract the common cold despite taking daily vitamin C supplements.
American Psychological Association (APA)
Ran, Li& Zhao, Wenli& Wang, Jingxia& Wang, Hongwu& Zhao, Ye& Tseng, Yiider…[et al.]. 2018. Extra Dose of Vitamin C Based on a Daily Supplementation Shortens the Common Cold: A Meta-Analysis of 9 Randomized Controlled Trials. BioMed Research International،Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1124686
Modern Language Association (MLA)
Ran, Li…[et al.]. Extra Dose of Vitamin C Based on a Daily Supplementation Shortens the Common Cold: A Meta-Analysis of 9 Randomized Controlled Trials. BioMed Research International No. 2018 (2018), pp.1-12.
https://search.emarefa.net/detail/BIM-1124686
American Medical Association (AMA)
Ran, Li& Zhao, Wenli& Wang, Jingxia& Wang, Hongwu& Zhao, Ye& Tseng, Yiider…[et al.]. Extra Dose of Vitamin C Based on a Daily Supplementation Shortens the Common Cold: A Meta-Analysis of 9 Randomized Controlled Trials. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1124686
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1124686