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A Nanomechanical Investigation of Engineered Bone Tissue Comparing Elastoplastic and Viscoelastoplastic Modeling
Joint Authors
Salamanna, Francesca
Sartori, Maria
Fini, Milena
Boi, Marco
Marchiori, Gregorio
Graziani, Gabriela
Russo, Alessandro
Visani, Andrea
Girolami, Mauro
Bianchi, Michele
Source
Advances in Materials Science and Engineering
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-08-27
Country of Publication
Egypt
No. of Pages
8
Abstract EN
It is common practice to implement the elastoplastic Oliver and Pharr (OP) model to investigate the spatial and temporal variations of mechanical properties of engineered bone.
However, the viscoelastoplastic (VEP) model may be preferred being envisaged to provide additional insights into the regeneration process, as it allows evaluating also the viscous content of bone tissue.
In this work, the elastic modulus (ER), contact hardness (HC), hardness (H), and viscosity index (ηQ) of newly formed bone tissue regenerated at 4 and 12 weeks from the implantation of a macroporous hydroxyapatite scaffold in a rabbit femoral critical-size model were addressed and compared to the mechanical properties of preexisting bone.
Indentation curves were fitted with both the OP and VEP models.
The VEP model outlined a wider gap between the mechanical properties of native and regenerated tissue when compared to the OP model.
In addition, the VEP model indicated an increase of the viscosity index from 4 to 12 weeks, supporting the evidence of a still active regeneration process.
The reported results confirmed the higher ability of VEP model compared to the more diffused OP model to provide important insights into bone mechanical properties, also during the bone regeneration process.
American Psychological Association (APA)
Boi, Marco& Marchiori, Gregorio& Sartori, Maria& Salamanna, Francesca& Graziani, Gabriela& Russo, Alessandro…[et al.]. 2017. A Nanomechanical Investigation of Engineered Bone Tissue Comparing Elastoplastic and Viscoelastoplastic Modeling. Advances in Materials Science and Engineering،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1124694
Modern Language Association (MLA)
Boi, Marco…[et al.]. A Nanomechanical Investigation of Engineered Bone Tissue Comparing Elastoplastic and Viscoelastoplastic Modeling. Advances in Materials Science and Engineering No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1124694
American Medical Association (AMA)
Boi, Marco& Marchiori, Gregorio& Sartori, Maria& Salamanna, Francesca& Graziani, Gabriela& Russo, Alessandro…[et al.]. A Nanomechanical Investigation of Engineered Bone Tissue Comparing Elastoplastic and Viscoelastoplastic Modeling. Advances in Materials Science and Engineering. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1124694
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1124694