Splenic Doppler Resistive Index Variation Mirrors Cardiac Responsiveness and Systemic Hemodynamics upon Fluid Challenge Resuscitation in Postoperative Mechanically Ventilated Patients
Joint Authors
Vezzani, Antonella
Manca, Tullio
Corradi, Francesco
Brusasco, Claudia
Santori, Gregorio
Tavazzi, Guido
Robba, Chiara
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-08-08
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Objective.
To test if splenic Doppler resistive index (SDRI) allows noninvasive monitoring of changes in stroke volume and regional splanchnic perfusion in response to fluid challenge.
Design and Setting.
Prospective observational study in cardiac intensive care unit.
Patients.
Fifty-three patients requiring mechanical ventilation and fluid challenge for hemodynamic optimization after cardiac surgery.
Interventions.
SDRI values were obtained before and after volume loading with 500 mL of normal saline over 20 min and compared with changes in systemic hemodynamics, determined invasively by pulmonary artery catheter, and arterial lactate concentration as expression of splanchnic perfusion.
Changes in stroke volume >10% were considered representative of fluid responsiveness.
Results.
A <4% SDRI reduction excluded fluid responsiveness, with 100% sensitivity and 100% negative predictive value.
A >9% SDRI reduction was a marker of fluid responsiveness with 100% specificity and 100% positive predictive value.
A >4% SDRI reduction was always associated with an improvement of splanchnic perfusion mirrored by an increase in lactate clearance and a reduction in systemic vascular resistance, regardless of fluid responsiveness.
Conclusions.
This study shows that SDRI variations after fluid administration is an effective noninvasive tool to monitor systemic hemodynamics and splanchnic perfusion upon volume administration, irrespective of fluid responsiveness in mechanically ventilated patients after cardiac surgery.
American Psychological Association (APA)
Brusasco, Claudia& Tavazzi, Guido& Robba, Chiara& Santori, Gregorio& Vezzani, Antonella& Manca, Tullio…[et al.]. 2018. Splenic Doppler Resistive Index Variation Mirrors Cardiac Responsiveness and Systemic Hemodynamics upon Fluid Challenge Resuscitation in Postoperative Mechanically Ventilated Patients. BioMed Research International،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1124812
Modern Language Association (MLA)
Brusasco, Claudia…[et al.]. Splenic Doppler Resistive Index Variation Mirrors Cardiac Responsiveness and Systemic Hemodynamics upon Fluid Challenge Resuscitation in Postoperative Mechanically Ventilated Patients. BioMed Research International No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1124812
American Medical Association (AMA)
Brusasco, Claudia& Tavazzi, Guido& Robba, Chiara& Santori, Gregorio& Vezzani, Antonella& Manca, Tullio…[et al.]. Splenic Doppler Resistive Index Variation Mirrors Cardiac Responsiveness and Systemic Hemodynamics upon Fluid Challenge Resuscitation in Postoperative Mechanically Ventilated Patients. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1124812
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1124812