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The Role of BPIFA1 in Upper Airway Microbial Infections and Correlated Diseases
Joint Authors
Tsai, Ming-Hsui
Chen, Chuan-Mu
Tsou, Yung-An
Chang, Wen-Dien
Tung, Min-Che
Alexander, Katherine A.
Chen, Hsiao-Ling
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-09-03
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
The mucosa is part of the first line of immune defense against pathogen exposure in humans and prevents viral and bacterial infection of the soft palate, lungs, uvula, and nasal cavity that comprise the ear-nose-throat (ENT) region.
Bactericidal/permeability-increasing fold containing family A, member 1 (BPIFA1) is a secretory protein found in human upper aerodigestive tract mucosa.
This innate material is secreted in mucosal fluid or found in submucosal tissue in the human soft palate, lung, uvula, and nasal cavity.
BPIFA1 is a critical component of the innate immune response that prevents upper airway diseases.
This review will provide a brief introduction of the roles of BPIFA1 in the upper airway (with a focus on the nasal cavity, sinus, and middle ear), specifically its history, identification, distribution in various human tissues, function, and diagnostic value in various upper airway infectious diseases.
American Psychological Association (APA)
Tsou, Yung-An& Tung, Min-Che& Alexander, Katherine A.& Chang, Wen-Dien& Tsai, Ming-Hsui& Chen, Hsiao-Ling…[et al.]. 2018. The Role of BPIFA1 in Upper Airway Microbial Infections and Correlated Diseases. BioMed Research International،Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1124834
Modern Language Association (MLA)
Tsou, Yung-An…[et al.]. The Role of BPIFA1 in Upper Airway Microbial Infections and Correlated Diseases. BioMed Research International No. 2018 (2018), pp.1-11.
https://search.emarefa.net/detail/BIM-1124834
American Medical Association (AMA)
Tsou, Yung-An& Tung, Min-Che& Alexander, Katherine A.& Chang, Wen-Dien& Tsai, Ming-Hsui& Chen, Hsiao-Ling…[et al.]. The Role of BPIFA1 in Upper Airway Microbial Infections and Correlated Diseases. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1124834
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1124834