A Normalized Shear Deformation Indicator for Ultrasound Strain Elastography in Breast Tissues: An In Vivo Feasibility Study
Joint Authors
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-02-12
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
The shear deformation under loads contains useful information for distinguishing benign breast lesions from malignant ones.
In this study, we proposed a normalized shear deformation indicator (NSDI) that was derived from the concept of principal strains.
Since the NSDI requires both high-quality axial and lateral (parallel and perpendicular to the beam, resp.) displacement estimates, a strategy combining high-quality speckle tracking with signal “denoising” was employed.
Both techniques were previously published by our group.
Finite element (FE) models were used to identify possible causes for elevated NSDI values in and around breast lesions, followed by an analysis of ultrasound data acquired from 26 biopsy-confirmed in vivo breast lesions.
We found that, theoretically, the elevated NSDI values could be attributed to two factors: significantly hardened tissue stiffness and increasing heterogeneity.
The analysis of in vivo data showed that the proposed NSDI values were higher (p<0.05) among malignant cancers as compared to those measured from benign ones.
In conclusion, our preliminary results demonstrated that the calculation of NSDI value is feasible and NSDI could add value to breast lesion differentiation with current clinical equipment as a postprocessing tool.
American Psychological Association (APA)
Jiang, Jingfeng& Peng, Bo. 2018. A Normalized Shear Deformation Indicator for Ultrasound Strain Elastography in Breast Tissues: An In Vivo Feasibility Study. BioMed Research International،Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1124856
Modern Language Association (MLA)
Jiang, Jingfeng& Peng, Bo. A Normalized Shear Deformation Indicator for Ultrasound Strain Elastography in Breast Tissues: An In Vivo Feasibility Study. BioMed Research International No. 2018 (2018), pp.1-11.
https://search.emarefa.net/detail/BIM-1124856
American Medical Association (AMA)
Jiang, Jingfeng& Peng, Bo. A Normalized Shear Deformation Indicator for Ultrasound Strain Elastography in Breast Tissues: An In Vivo Feasibility Study. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1124856
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1124856