Evaluation of the Spermatogenic Activity of Polyherbal Formulation in Oligospermic Males
Joint Authors
Hussain, Syed Ammar
Hameed, Ahsan
Nasir, Furqan
Wu, Yang
Suleria, Hafiz Ansar Rasul
Song, Yuanda
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-07-25
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The therapeutic use of natural herbs is an ancient human civilization act and the numbers of people have reliance on their pharmacological properties and preferred to use the natural herbs.
People also use to consume these herbs as supplements to energize, bolster, and eventually enhance sexual ability.
Polyherbal formulation (PHF) is one of these herbal amalgams that can be used to treat sexual dysfunction including erectile dysfunction, impotence, ejaculation dysfunction, and hypogonadism.
The pilot study was aimed at evaluating the capacity of PHF in enhancing the spermatogenic potential of oligospermic patients.
Thirty-six male patients with oligospermia were enrolled and randomized either to treatment (n = 23) with PHF (750 mg/d in three doses for 90 days) or to placebo (n = 13) in the same protocol.
The preintervention semen analysis was compared with posttreatment semen analysis.
Based on the postintervention semen analysis, patients were advised to undergo either in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) to assess their fertility status.
After polyherbal treatment, there was a 256% increase in sperm concentration (9.59±4.37×106/mL to 25.61±8.6×106/mL; P ≤0.001), 154% increase in semen volume (1.7±0.14 mL to 4.32±0.38 mL; P ≤0.001), and 215% increase in sperm motility (15.43±2.40% to 48.65±5.10%; P ≤ 0.001) on day 90 from baseline.
Furthermore, a significant improvement and regulation were also observed in serum hormone levels with PHF treatment as compared to the placebo group.
The present study demonstrated the evidence on synergistic spermatogenic effect of PHF as attributed in ayurveda for the treatment of oligospermia leading to infertility.
American Psychological Association (APA)
Hussain, Syed Ammar& Hameed, Ahsan& Nasir, Furqan& Wu, Yang& Suleria, Hafiz Ansar Rasul& Song, Yuanda. 2018. Evaluation of the Spermatogenic Activity of Polyherbal Formulation in Oligospermic Males. BioMed Research International،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1124871
Modern Language Association (MLA)
Hussain, Syed Ammar…[et al.]. Evaluation of the Spermatogenic Activity of Polyherbal Formulation in Oligospermic Males. BioMed Research International No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1124871
American Medical Association (AMA)
Hussain, Syed Ammar& Hameed, Ahsan& Nasir, Furqan& Wu, Yang& Suleria, Hafiz Ansar Rasul& Song, Yuanda. Evaluation of the Spermatogenic Activity of Polyherbal Formulation in Oligospermic Males. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1124871
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1124871