The Association of Perioperative Serum Lactate Levels with Postoperative Delirium in Elderly Trauma Patients
Joint Authors
Lee, Cheol
Cho, Hyunho
Song, Jaekyeong
Jung, Hojung
Ma, Xiao
Hwang, Jihyo
Lee, Ju Hwan
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-11-16
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Several studies have shown the utility of lactate level as a predictor of early outcomes in trauma patients.
We conducted this study to evaluate the association of perioperative serum lactate levels with postoperative delirium (POD) in elderly trauma patients.
Materials and Methods.
This study included 466 elderly trauma patients with measurements of serum lactate levels on admission and 1 h after surgery.
The associations of POD with serum lactate levels (on admission and 1 h after surgery) and lactate clearance were analyzed using Kendall’s correlation.
Perioperative serum lactate levels and lactate clearance as predictors of POD were evaluated using univariate and multivariable analyses.
Results.
The incidence of POD in the present study was 38.1%.
Serum lactate levels on admission and at 1 h after surgery were significantly higher in major trauma than in minor trauma.
In univariate analysis of perioperative serum lactate levels and lactate clearance as predictors of POD, the odds ratio (OR) for serum lactate level on admission was 4.19 (P<0.01, 2.91 < 95% confidence interval (CI) < 6.02) and that 1 h after surgery was 3.83 (P<0.01, 2.79 < 95% CI < 5.25); however, the OR for serum change of lactate level was 0.99 ((P<0.09, 0.99 < 95% CI < 1.00).
In multivariable analysis for predictors of POD, the OR for serum lactate level on admission was 2.40 (P<0.09, 0.87 < 95% CI < 6.7), that for serum lactate 1 h after surgery was 2.83 (P=0.01, 1.28 < 95% CI < 6.24), that for ICU admission was 3.01 (P=0.01, 2.09 < 95% CI < 6.03), and that for ISS was 1.47 (P<0.01, 1.27 < 95% CI < 3.70).
Conclusions.
Taking together the results of univariate and multivariable analyses, serum lactate level 1 h after surgery may be used as a prediction model of POD development in elderly trauma patients.
American Psychological Association (APA)
Lee, Cheol& Lee, Ju Hwan& Cho, Hyunho& Song, Jaekyeong& Jung, Hojung& Ma, Xiao…[et al.]. 2019. The Association of Perioperative Serum Lactate Levels with Postoperative Delirium in Elderly Trauma Patients. BioMed Research International،Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1125021
Modern Language Association (MLA)
Lee, Cheol…[et al.]. The Association of Perioperative Serum Lactate Levels with Postoperative Delirium in Elderly Trauma Patients. BioMed Research International No. 2019 (2019), pp.1-7.
https://search.emarefa.net/detail/BIM-1125021
American Medical Association (AMA)
Lee, Cheol& Lee, Ju Hwan& Cho, Hyunho& Song, Jaekyeong& Jung, Hojung& Ma, Xiao…[et al.]. The Association of Perioperative Serum Lactate Levels with Postoperative Delirium in Elderly Trauma Patients. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1125021
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1125021