Current Advances on the Important Roles of Enhancer RNAs in Gene Regulation and Cancer
Joint Authors
Liu, Yuhan
Ding, Mengting
Gao, Qunjun
He, Anbang
Liu, Yuchen
Mei, Hongbing
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-05-22
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Revealing the gene regulation networks governing cancer initiation and development is necessary while it remains uncompleted.
In recent years, enhancers have been reported to be widely transcribed, resulting in the generation of enhancer RNAs (eRNAs).
Previous studies have reported that eRNAs are a subclass of long noncoding RNAs (lncRNAs), which play a critical role in gene regulation and cancer development.
These eRNAs can promote enhancer-promoter (E-P) looping formation by binding to other protein factors or propel expression of downstream protein-coding gene.
In this review, we have focused on the characteristics of eRNAs and illustrated the biological function and potential mechanism of eRNAs in regulating gene expression and cancer development.
American Psychological Association (APA)
Liu, Yuhan& Ding, Mengting& Gao, Qunjun& He, Anbang& Liu, Yuchen& Mei, Hongbing. 2018. Current Advances on the Important Roles of Enhancer RNAs in Gene Regulation and Cancer. BioMed Research International،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1125027
Modern Language Association (MLA)
Liu, Yuhan…[et al.]. Current Advances on the Important Roles of Enhancer RNAs in Gene Regulation and Cancer. BioMed Research International No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1125027
American Medical Association (AMA)
Liu, Yuhan& Ding, Mengting& Gao, Qunjun& He, Anbang& Liu, Yuchen& Mei, Hongbing. Current Advances on the Important Roles of Enhancer RNAs in Gene Regulation and Cancer. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1125027
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1125027