The Relationship between Serum Zinc Level and Heart Failure: A Meta-Analysis
Joint Authors
Yu, Xuefang
Huang, Lei
Zhao, Jinyan
Wang, Zhuoqun
Yao, Wei
Wu, Xianming
Huang, Jingjing
Bian, Bo
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-02-25
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Zinc is essential for the maintenance of normal cellular structure and functions.
Zinc dyshomeostasis can lead to many diseases, such as cardiovascular disease.
However, there are conflicting reports on the relationship between serum zinc levels and heart failure (HF).
The purpose of the present study is to explore the relationship between serum zinc levels and HF by using a meta-analysis approach.
PubMed, Web of Science, and OVID databases were searched for reports on the association between serum zinc levels and HF until June 2016.
12 reports with 1453 subjects from 27 case-control studies were chosen for the meta-analysis.
Overall, the pooled analysis indicated that patients with HF had lower zinc levels than the control subjects.
Further subgroup analysis stratified by different geographic locations also showed that HF patients had lower zinc levels than the control subjects.
In addition, subgroup analysis stratified by HF subgroups found that patients with idiopathic dilated cardiomyopathy (IDCM) had lower zinc levels than the control subjects, except for patients with ischemic cardiomyopathy (ICM).
In conclusion, the results of the meta-analysis indicate that there is a significant association between low serum zinc levels and HF.
American Psychological Association (APA)
Yu, Xuefang& Huang, Lei& Zhao, Jinyan& Wang, Zhuoqun& Yao, Wei& Wu, Xianming…[et al.]. 2018. The Relationship between Serum Zinc Level and Heart Failure: A Meta-Analysis. BioMed Research International،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1125289
Modern Language Association (MLA)
Yu, Xuefang…[et al.]. The Relationship between Serum Zinc Level and Heart Failure: A Meta-Analysis. BioMed Research International No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1125289
American Medical Association (AMA)
Yu, Xuefang& Huang, Lei& Zhao, Jinyan& Wang, Zhuoqun& Yao, Wei& Wu, Xianming…[et al.]. The Relationship between Serum Zinc Level and Heart Failure: A Meta-Analysis. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1125289
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1125289