MicroRNA-Mediated Regulation of HMGB1 in Human Hepatocellular Carcinoma
Joint Authors
Ying, Shibo
Yan, Jianing
Cai, Xiujun
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-01-31
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
High-mobility group box 1 (HMGB1) is a potential therapeutic target and novel biomarker in a variety of malignant tumors, including hepatocellular carcinoma (HCC).
More recently, a number of microRNAs (miRNAs) are identified as a class of regulators for broad control of HMGB1-mediated biological actions in eukaryotic cells.
In this review article we will describe representative miRNAs involved in regulating the HMGB1 signaling pathways in HCC cell lines and/or animal models.
We also propose the possible mechanisms underlying the miRNA/HMGB1 axis and discuss the future clinical significance of miRNAs targeting HMGB1 molecule for HCC therapy.
American Psychological Association (APA)
Yan, Jianing& Ying, Shibo& Cai, Xiujun. 2018. MicroRNA-Mediated Regulation of HMGB1 in Human Hepatocellular Carcinoma. BioMed Research International،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1125311
Modern Language Association (MLA)
Yan, Jianing…[et al.]. MicroRNA-Mediated Regulation of HMGB1 in Human Hepatocellular Carcinoma. BioMed Research International No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1125311
American Medical Association (AMA)
Yan, Jianing& Ying, Shibo& Cai, Xiujun. MicroRNA-Mediated Regulation of HMGB1 in Human Hepatocellular Carcinoma. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1125311
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1125311
