![](/images/graphics-bg.png)
Jiedu Granule Combined with Transcatheter Arterial Chemoembolization and Gamma Knife Radiosurgery in Treating Hepatocellular Carcinoma with Portal Vein Tumor Thrombus
Joint Authors
Wang, Jianchu
Luo, Jinhong
Yin, Xiaolan
Huang, Wei
Cao, Huangming
Wang, Guilin
Wang, Jincheng
Zhou, Jun
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-06-25
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
The potential advantages of Jiedu granule (a compound Chinese herbal medicine) combined therapeutic strategies compared with non-Jiedu granule therapeutic strategies for hepatocellular carcinoma (HCC) with portal vein tumor thrombosis (PVTT) remain unclear.
Thus, the purpose of the study was to investigate the safety and efficacy of Jiedu granule for HCC with PVTT.
Methods.
We retrospectively reviewed the clinical data of 190 patients (94 for non-Jiedu and 96 for Jiedu) with HCC and PVTT from March 2012 to October 2016.
Patients were followed up by outpatient examination and telephone till November 2018.
Results.
It was statistically insignificant between the two groups in baseline characteristics.
Procedure-related adverse events (AEs) were observed and compared and most of them were not serious which were easily controlled or subsided naturally.
No AE-induced death happened.
The median overall survival (OS) rates in the single TACE plus GKR and Jiedu granule combined group were 11.3 months (95% CI: 9.168-13.435) and 15.8 months (95% CI: 13.244-18.339), respectively (p = 0.00047).
Conclusions.
Jiedu granule combined with TACE plus GKR is safe in HCC patients with PVTT and this Chinese herbal medicine is worthy to be promoted because of better prognosis which needs further research.
American Psychological Association (APA)
Wang, Jianchu& Luo, Jinhong& Yin, Xiaolan& Huang, Wei& Cao, Huangming& Wang, Guilin…[et al.]. 2019. Jiedu Granule Combined with Transcatheter Arterial Chemoembolization and Gamma Knife Radiosurgery in Treating Hepatocellular Carcinoma with Portal Vein Tumor Thrombus. BioMed Research International،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1125531
Modern Language Association (MLA)
Wang, Jianchu…[et al.]. Jiedu Granule Combined with Transcatheter Arterial Chemoembolization and Gamma Knife Radiosurgery in Treating Hepatocellular Carcinoma with Portal Vein Tumor Thrombus. BioMed Research International No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1125531
American Medical Association (AMA)
Wang, Jianchu& Luo, Jinhong& Yin, Xiaolan& Huang, Wei& Cao, Huangming& Wang, Guilin…[et al.]. Jiedu Granule Combined with Transcatheter Arterial Chemoembolization and Gamma Knife Radiosurgery in Treating Hepatocellular Carcinoma with Portal Vein Tumor Thrombus. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1125531
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1125531