Burkholderia pseudomallei Adaptation for Survival in Stressful Conditions
Joint Authors
Indrawattana, N.
Duangurai, Taksaon
Pumirat, Pornpan
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-05-27
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Burkholderia pseudomallei is a Gram-negative bacterium that causes melioidosis, which can be fatal in humans.
Melioidosis is prevalent in the tropical regions of Southeast Asia and Northern Australia.
Ecological data have shown that this bacterium can survive as a free-living organism in environmental niches, such as soil and water, as well as a parasite living in host organisms, such as ameba, plants, fungi, and animals.
This review provides an overview of the survival and adaptation of B.
pseudomallei to stressful conditions induced by hostile environmental factors, such as salinity, oxidation, and iron levels.
The adaptation of B.
pseudomallei in host cells is also reviewed.
The adaptive survival mechanisms of this pathogen mainly involve modulation of gene and protein expression, which could cause alterations in the bacteria’s cell membrane, metabolism, and virulence.
Understanding the adaptations of this organism to environmental factors provides important insights into the survival and pathogenesis of B.
pseudomallei, which may lead to the development of novel strategies for the control, prevention, and treatment of melioidosis in the future.
American Psychological Association (APA)
Duangurai, Taksaon& Indrawattana, N.& Pumirat, Pornpan. 2018. Burkholderia pseudomallei Adaptation for Survival in Stressful Conditions. BioMed Research International،Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1125578
Modern Language Association (MLA)
Duangurai, Taksaon…[et al.]. Burkholderia pseudomallei Adaptation for Survival in Stressful Conditions. BioMed Research International No. 2018 (2018), pp.1-11.
https://search.emarefa.net/detail/BIM-1125578
American Medical Association (AMA)
Duangurai, Taksaon& Indrawattana, N.& Pumirat, Pornpan. Burkholderia pseudomallei Adaptation for Survival in Stressful Conditions. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1125578
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1125578