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Bacterial Aetiologies of Lower Respiratory Tract Infections among Adults in Yaoundé, Cameroon
Joint Authors
Tchatchouang, Serges
Nzouankeu, Ariane
Kenmoe, Sebastien
Ngando, Laure
Penlap, Veronique
Fonkoua, Marie-Christine
Pefura-Yone, Eric-Walter
Njouom, Richard
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-04-17
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Lower respiratory tract infections (LRTIs) remain a challenge in African healthcare settings and only few data are available on their aetiology in Cameroon.
The purpose of this study was to access the bacterial cause of LRTIs in patients in Cameroon by two methods.
Methods.
Participants with LRTIs were enrolled in the referral centre for respiratory diseases in Yaoundé city and its surroundings.
To detect bacteria, specimens were tested by conventional bacterial culture and a commercial reverse-transcriptase real-time polymerase chain reaction (RT-PCR) assay.
One hundred forty-one adult patients with LRTIs were enrolled in the study.
Among the participants, 46.8% were positive for at least one bacterium.
Streptococcus pneumoniae and Haemophilus influenzae were the most detected bacteria with 14.2% (20/141) followed by Klebsiella pneumoniae, 9.2% (13/141), Staphylococcus aureus, 7.1% (10/141), and Moraxella catarrhalis, 4.3% (6/141).
Bacterial coinfection accounted for 23% (14/61) with Haemophilus influenzae being implicated in 19.7% (12/61).
The diagnostic performance of RT-PCR for bacteria detection (43.3%) was significantly different from that of culture (17.7%) (p< 0.001).
Only Streptococcus pneumoniae detection was associated with empyema by RT-PCR (p<0.001).
These findings enhance understanding of bacterial aetiologies in order to improve respiratory infection management and treatment.
It also highlights the need to implement molecular tools as part of the diagnosis of LRTIs.
American Psychological Association (APA)
Tchatchouang, Serges& Nzouankeu, Ariane& Kenmoe, Sebastien& Ngando, Laure& Penlap, Veronique& Fonkoua, Marie-Christine…[et al.]. 2019. Bacterial Aetiologies of Lower Respiratory Tract Infections among Adults in Yaoundé, Cameroon. BioMed Research International،Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1125638
Modern Language Association (MLA)
Tchatchouang, Serges…[et al.]. Bacterial Aetiologies of Lower Respiratory Tract Infections among Adults in Yaoundé, Cameroon. BioMed Research International No. 2019 (2019), pp.1-7.
https://search.emarefa.net/detail/BIM-1125638
American Medical Association (AMA)
Tchatchouang, Serges& Nzouankeu, Ariane& Kenmoe, Sebastien& Ngando, Laure& Penlap, Veronique& Fonkoua, Marie-Christine…[et al.]. Bacterial Aetiologies of Lower Respiratory Tract Infections among Adults in Yaoundé, Cameroon. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1125638
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1125638