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A Comparison of Traditional and Novel Methods for the Separation of Exosomes from Human Samples
Joint Authors
Yu, Li-Li
Zhu, Jing
Liu, Jin-Xia
Jiang, Feng
Ni, Wen-Kai
Qu, Li-Shuai
Ni, Run-Zhou
Lu, Cui-Hua
Xiao, Ming-Bing
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-07-26
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Exosomes are discrete populations of small (40-200 nm in diameter) membranous vesicles that are released into the extracellular space by most cell types, eventually accumulating in the circulation.
As molecular messengers, exosomes exert a broad array of vital physiologic functions by transporting information between different cell types.
Because of these functional properties, they may have potential as biomarker sources for prognostic and diagnostic disease.
Recent research has found that exosomes have potential to be utilized as drug delivery agents for therapeutic targets.
However, basic researches on exosomes and researches on their therapeutic potential both require the existence of effective and rapid methods for their separation from human samples.
In the current absence of a standardized method, there are several methods available for the separation of exosomes, but very few studies have previously compared the efficiency and suitability of these different methods.
This review summarized and compared the available traditional and novel methods for the extraction of exosomes from human samples and considered their advantages and disadvantages for use in clinical laboratories and point-of-care settings.
American Psychological Association (APA)
Yu, Li-Li& Zhu, Jing& Liu, Jin-Xia& Jiang, Feng& Ni, Wen-Kai& Qu, Li-Shuai…[et al.]. 2018. A Comparison of Traditional and Novel Methods for the Separation of Exosomes from Human Samples. BioMed Research International،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1125980
Modern Language Association (MLA)
Yu, Li-Li…[et al.]. A Comparison of Traditional and Novel Methods for the Separation of Exosomes from Human Samples. BioMed Research International No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1125980
American Medical Association (AMA)
Yu, Li-Li& Zhu, Jing& Liu, Jin-Xia& Jiang, Feng& Ni, Wen-Kai& Qu, Li-Shuai…[et al.]. A Comparison of Traditional and Novel Methods for the Separation of Exosomes from Human Samples. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1125980
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1125980