The Bidirectional Interactions between Resveratrol and Gut Microbiota: An Insight into Oxidative Stress and Inflammatory Bowel Disease Therapy
Joint Authors
Mao, Xiangbing
He, Jun
Yu, Bing
Chen, Daiwen
Hu, Yaolian
Zheng, Ping
Yu, Jie
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-04-24
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Dysbiosis and oxidative stress in the gut have contributed to the progression of intestinal inflammatory bowel disease (IBD).
The current study has reported that enteric bacteria mediate redox homeostasis through the regulation of reactive oxygen species (ROS) production.
Resveratrol, one of the most abundant polyphenols, with poor oral bioavailability, is considered as a scavenger of ROS and other free radicals.
Recent studies have shown that resveratrol effectively enhances the growth of Lactococcus lactis and inhibits the growth of Enterococcus faecalis.
(1) In terms of the two-way relationship between gut microbiota and resveratrol, resveratrol modulates gut microbiota; (2) in terms of resveratrol biotransformation by gut microbiota, we speculate that gut microbiota could be a target of resveratrol to maintain gut homeostasis.
Here, we reviewed the current researches about the cellular signaling pathways in intestinal epithelial cells triggered by gut microbiota in response to oxidative stress.
These results suggest that the modulation of the gut microbiota through resveratrol supplementation appears as a promising potential approach for the therapy of inflammatory bowel disease.
American Psychological Association (APA)
Hu, Yaolian& Chen, Daiwen& Zheng, Ping& Yu, Jie& He, Jun& Mao, Xiangbing…[et al.]. 2019. The Bidirectional Interactions between Resveratrol and Gut Microbiota: An Insight into Oxidative Stress and Inflammatory Bowel Disease Therapy. BioMed Research International،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1126009
Modern Language Association (MLA)
Hu, Yaolian…[et al.]. The Bidirectional Interactions between Resveratrol and Gut Microbiota: An Insight into Oxidative Stress and Inflammatory Bowel Disease Therapy. BioMed Research International No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1126009
American Medical Association (AMA)
Hu, Yaolian& Chen, Daiwen& Zheng, Ping& Yu, Jie& He, Jun& Mao, Xiangbing…[et al.]. The Bidirectional Interactions between Resveratrol and Gut Microbiota: An Insight into Oxidative Stress and Inflammatory Bowel Disease Therapy. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1126009
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1126009