Long Noncoding RNA in Preeclampsia: Transcriptional Noise or Innovative Indicators?
Joint Authors
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-04-14
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Preeclampsia (PE) is termed as an obstetric issue that is characterized by hypertension (≧140/90 mm Hg), together with proteinuria following 20 weeks of pregnancy.
Until today, PE still constitutes a severe threat to the lives of both the mothers and fetuses.
In the past, long noncoding RNAs (lncRNAs) were considered as the transcriptional noise.
However, some investigations have indicated that lncRNAs could be used as innovative indicators in PE.
The current review aims to discuss the relationship between lncRNAs and PE in recent years.
According to the retrieved data, we concluded that lncRNAs can exert an impact on both the occurrence and development of PE through the changes in the biological functions of trophoblasts, immune regulation, epigenetic regulation, decidualization, and energy metabolism.
The mechanisms of lncRNAs in PE will help us to better understand the pathogenesis of PE and help us to find targets for predicting and diagnosing PE in the future.
American Psychological Association (APA)
Yang, Xiuhua& Meng, Tao. 2019. Long Noncoding RNA in Preeclampsia: Transcriptional Noise or Innovative Indicators?. BioMed Research International،Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1126043
Modern Language Association (MLA)
Yang, Xiuhua& Meng, Tao. Long Noncoding RNA in Preeclampsia: Transcriptional Noise or Innovative Indicators?. BioMed Research International No. 2019 (2019), pp.1-7.
https://search.emarefa.net/detail/BIM-1126043
American Medical Association (AMA)
Yang, Xiuhua& Meng, Tao. Long Noncoding RNA in Preeclampsia: Transcriptional Noise or Innovative Indicators?. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1126043
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1126043