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Lectins as Promising Therapeutics for the Prevention and Treatment of HIV and Other Potential Coinfections
Joint Authors
Mazalovska, Milena
Kouokam, J. Calvin
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-05-08
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Human immunodeficiency virus-acquired immunodeficiency syndrome (HIV/AIDS) remains a global health problem.
Current therapeutics specifically target the viral pathogen at various stages of its life cycle, although complex interactions between HIV and other pathogenic organisms are evident.
Targeting HIV and concomitant infectious pathogens simultaneously, both by therapeutic regimens and in prevention strategies, would help contain the AIDS pandemic.
Lectins, a ubiquitous group of proteins that specifically bind glycosylated molecules, are interesting compounds that could be used for this purpose, with demonstrated anti-HIV properties.
In addition, potential coinfecting pathogens, including other enveloped viruses, bacteria, yeasts and fungi, and protozoa, display sugar-coated macromolecules on their surfaces, making them potential targets of lectins.
This review summarizes the currently available findings suggesting that lectins should be further developed to simultaneously fight the AIDS pandemic and concomitant infections in HIV infected individuals.
American Psychological Association (APA)
Mazalovska, Milena& Kouokam, J. Calvin. 2018. Lectins as Promising Therapeutics for the Prevention and Treatment of HIV and Other Potential Coinfections. BioMed Research International،Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1126069
Modern Language Association (MLA)
Mazalovska, Milena& Kouokam, J. Calvin. Lectins as Promising Therapeutics for the Prevention and Treatment of HIV and Other Potential Coinfections. BioMed Research International No. 2018 (2018), pp.1-12.
https://search.emarefa.net/detail/BIM-1126069
American Medical Association (AMA)
Mazalovska, Milena& Kouokam, J. Calvin. Lectins as Promising Therapeutics for the Prevention and Treatment of HIV and Other Potential Coinfections. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1126069
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1126069