Physiological and Pathological Function of SerineArginine-Rich Splicing Factor 4 and Related Diseases
Joint Authors
Tan, Wanyan
Wang, Wei
Ma, Qingfeng
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-02-12
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Serine/arginine-rich splicing factors (SRSFs) have one or two RNA recognition motifs in the N terminal and a serine/arginine-enriched domain in the C terminal.
SRSFs are essential components of spliceosomes and are involved in alternative splicing, spliceosome assembly, mRNA export, and nonsense-mediated mRNA decay.
The maintenance of cellular and tissue homeostasis relies on accurate alternative splicing, and various patterns of abnormal alternative splicing can cause different diseases.
SRSF4 is associated with many physiological and pathological processes and has applications in the diagnosis and prognosis of specific diseases.
In this review, we discuss knowledge of SRSF4 in physiological and pathological processes and highlight the applications of SRSF4 in the regulation of gene expression and associated diseases.
American Psychological Association (APA)
Tan, Wanyan& Wang, Wei& Ma, Qingfeng. 2018. Physiological and Pathological Function of SerineArginine-Rich Splicing Factor 4 and Related Diseases. BioMed Research International،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1126127
Modern Language Association (MLA)
Tan, Wanyan…[et al.]. Physiological and Pathological Function of SerineArginine-Rich Splicing Factor 4 and Related Diseases. BioMed Research International No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1126127
American Medical Association (AMA)
Tan, Wanyan& Wang, Wei& Ma, Qingfeng. Physiological and Pathological Function of SerineArginine-Rich Splicing Factor 4 and Related Diseases. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1126127
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1126127