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Effects and Mechanisms of Tastants on the Gustatory-Salivary Reflex in Human Minor Salivary Glands
Joint Authors
Sasano, Takashi
Satoh-Kuriwada, Shizuko
Shoji, Noriaki
Miyake, Hiroyuki
Watanabe, Chiyo
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-01-31
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
The effects and mechanisms of tastes on labial minor salivary gland (LMSG) secretion were investigated in 59 healthy individuals.
Stimulation with each of the five basic tastes (i.e., sweet, salty, sour, bitter, and umami) onto the tongue induced LMSG secretion in a dose-dependent manner.
Umami and sour tastes evoked greater secretion than did the other tastes.
A synergistic effect of umami on LMSG secretion was recognized: a much greater increase in secretion was observed by a mixed solution of monosodium glutamate and inosine 5′-monophosphate than by each separate stimulation.
Blood flow (BF) in the nearby labial mucosa also increased following stimulation by each taste except bitter.
The BF change and LMSG secretion in each participant showed a significant positive correlation with all tastes, including bitter.
Administration of cevimeline hydrochloride hydrate to the labial mucosa evoked a significant increase in both LMSG secretion and BF, while adrenaline, atropine, and pirenzepine decreased LMSG secretion and BF.
The change in LMSG secretion and BF induced by each autonomic agent was significantly correlated in each participant.
These results indicate that basic tastes can induce the gustatory-salivary reflex in human LMSGs and that parasympathetic regulation is involved in this mechanism.
American Psychological Association (APA)
Satoh-Kuriwada, Shizuko& Shoji, Noriaki& Miyake, Hiroyuki& Watanabe, Chiyo& Sasano, Takashi. 2018. Effects and Mechanisms of Tastants on the Gustatory-Salivary Reflex in Human Minor Salivary Glands. BioMed Research International،Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1126157
Modern Language Association (MLA)
Satoh-Kuriwada, Shizuko…[et al.]. Effects and Mechanisms of Tastants on the Gustatory-Salivary Reflex in Human Minor Salivary Glands. BioMed Research International No. 2018 (2018), pp.1-12.
https://search.emarefa.net/detail/BIM-1126157
American Medical Association (AMA)
Satoh-Kuriwada, Shizuko& Shoji, Noriaki& Miyake, Hiroyuki& Watanabe, Chiyo& Sasano, Takashi. Effects and Mechanisms of Tastants on the Gustatory-Salivary Reflex in Human Minor Salivary Glands. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1126157
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1126157