Cellular and Extracellular Components in Tumor Microenvironment and Their Application in Early Diagnosis of Cancers
Joint Authors
Zhu, Shengtao
Liu, Si
Zhang, Shutian
Min, Li
Wei, Rui
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-01-08
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Tumors are surrounded by complex environmental components, including blood and lymph vessels, fibroblasts, endothelial cells, immune cells, cytokines, extracellular vesicles, and extracellular matrix.
All the stromal components together with the tumor cells form the tumor microenvironment (TME).
In addition, extracellular physical and chemical factors, including extracellular pH, hypoxia, elevated interstitial fluid pressure, and fibrosis, are closely associated with tumor progression, metastasis, immunosuppression, and drug resistance.
Cellular and extracellular components in TME contribute to nearly all procedures of carcinogenesis.
By summarizing the recent work in this field, we make a comprehensive review on the role of cellular and extracellular components in the process of carcinogenesis and their potential application in early diagnosis of cancer.
We hope that a systematic review of the diverse aspects of TME will help both research scientists and clinicians in this field.
American Psychological Association (APA)
Wei, Rui& Liu, Si& Zhang, Shutian& Min, Li& Zhu, Shengtao. 2020. Cellular and Extracellular Components in Tumor Microenvironment and Their Application in Early Diagnosis of Cancers. Analytical Cellular Pathology،Vol. 2020, no. 2020, pp.1-13.
https://search.emarefa.net/detail/BIM-1126186
Modern Language Association (MLA)
Wei, Rui…[et al.]. Cellular and Extracellular Components in Tumor Microenvironment and Their Application in Early Diagnosis of Cancers. Analytical Cellular Pathology No. 2020 (2020), pp.1-13.
https://search.emarefa.net/detail/BIM-1126186
American Medical Association (AMA)
Wei, Rui& Liu, Si& Zhang, Shutian& Min, Li& Zhu, Shengtao. Cellular and Extracellular Components in Tumor Microenvironment and Their Application in Early Diagnosis of Cancers. Analytical Cellular Pathology. 2020. Vol. 2020, no. 2020, pp.1-13.
https://search.emarefa.net/detail/BIM-1126186
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1126186