![](/images/graphics-bg.png)
Health-Related Quality of Life in Pulmonary Hypertension and Its Clinical Correlates: A Cross-Sectional Study
Joint Authors
Gonçalves, Fabienne
Reis, Abílio
Santos, Mário
Vicente, Margarida
Furtado, Inês
Cruz, Célia
Melo, Alzira
Carvalho, Luísa
Almeida, Luís
Sá-Couto, Pedro
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-03-19
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Background.
Health-related quality of life (HRQoL) impairment is common in pulmonary hypertension (PH), but its clinical predictors are not well established.
This study aims to characterize the HRQoL of patients with pulmonary arterial hypertension (PAH) and other precapillary forms of PH (pcPH) and to explore its clinical correlates.
Materials and Methods.
A cross-sectional, observational study of patients with documented PAH and other forms of pcPH.
Patients completed two patient-reported outcome measures (PROM): Cambridge Pulmonary Hypertension Outcome Review (CAMPHOR) and Nottingham Health Profile (NHP).
Clinical characteristics were retrieved from electronic medical records.
Results.
Mean CAMPHOR and NHP scores for the study population were indicative of a moderate HRQoL impairment.
Patients in World Health Organisation Functional Classes (WHO FC) III/IV showed significantly worse HRQoL.
The main clinical correlates of HRQoL were WHO FC, 6-minute walking distance (6MWD), and Borg dyspnoea index.
Overall quality of life (QoL), assessed through CAMPHOR’s QoL domain, showed patterns comparable to HRQoL measured by both instruments.
Conclusions.
HRQoL, measured by two different PROMs, is impaired in Portuguese patients with PAH and other forms of pcPH, particularly in patients with increased disease severity.
WHO FC, 6MWD, and Borg dyspnoea index are highly correlated with HRQoL and QoL.
American Psychological Association (APA)
Reis, Abílio& Santos, Mário& Vicente, Margarida& Furtado, Inês& Cruz, Célia& Melo, Alzira…[et al.]. 2018. Health-Related Quality of Life in Pulmonary Hypertension and Its Clinical Correlates: A Cross-Sectional Study. BioMed Research International،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1126227
Modern Language Association (MLA)
Reis, Abílio…[et al.]. Health-Related Quality of Life in Pulmonary Hypertension and Its Clinical Correlates: A Cross-Sectional Study. BioMed Research International No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1126227
American Medical Association (AMA)
Reis, Abílio& Santos, Mário& Vicente, Margarida& Furtado, Inês& Cruz, Célia& Melo, Alzira…[et al.]. Health-Related Quality of Life in Pulmonary Hypertension and Its Clinical Correlates: A Cross-Sectional Study. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1126227
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1126227