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Potential Anticancer Properties and Mechanisms of Action of Formononetin
Joint Authors
Ali, M.
Hussain, Ghulam
Rasul, Azhar
Selamoglu, Zeliha
Li, Xiaomeng
Sarfraz, Iqra
Jiang, Dongjun
Batool, Rabia
Mateen Tahir, Muhammad
Qin, Tian
Li, Jiang
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-07-28
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Nature, a vast reservoir of pharmacologically active molecules, has been most promising source of drug leads for the cure of various pathological conditions.
Formononetin is one of the bioactive isoflavones isolated from different plants mainly from Trifolium pratense, Glycine max, Sophora flavescens, Pycnanthus angolensis, and Astragalus membranaceus.
Formononetin has been well-documented for its anti-inflammatory, anticancer, and antioxidant properties.
Recently anticancer activity of formononetin is widely studied.
This review aims to highlight the pharmacological potential of formononetin, thus providing an insight of its status in cancer therapeutics.
Formononetin fights progression of cancer via inducing apoptosis, arresting cell cycle, and halting metastasis via targeting various pathways which are generally modulated in several cancers.
Although reported data acclaims various biological properties of formononetin, further experimentation on mechanism of its action, medicinal chemistry studies, and preclinical investigations are surely needed to figure out full array of its pharmacological and biological potential.
American Psychological Association (APA)
Jiang, Dongjun& Rasul, Azhar& Batool, Rabia& Sarfraz, Iqra& Hussain, Ghulam& Mateen Tahir, Muhammad…[et al.]. 2019. Potential Anticancer Properties and Mechanisms of Action of Formononetin. BioMed Research International،Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1126280
Modern Language Association (MLA)
Jiang, Dongjun…[et al.]. Potential Anticancer Properties and Mechanisms of Action of Formononetin. BioMed Research International No. 2019 (2019), pp.1-11.
https://search.emarefa.net/detail/BIM-1126280
American Medical Association (AMA)
Jiang, Dongjun& Rasul, Azhar& Batool, Rabia& Sarfraz, Iqra& Hussain, Ghulam& Mateen Tahir, Muhammad…[et al.]. Potential Anticancer Properties and Mechanisms of Action of Formononetin. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1126280
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1126280