Could the Combined Administration of Bone Antiresorptive Drug, Taxanes, and Corticosteroids Worsen Medication Related Osteonecrosis of the Jaws in Cancer Patients?
Joint Authors
Oteri, Giacomo
Campisi, G.
Di Fede, O.
Panzarella, Vera
Morreale, Ilaria
Nucera, Riccardo
Picone, Antonio
Marcianò, Antonia
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-05-29
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The study presents a report of 58 metastatic cancer patients who developed osteonecrosis of the jaws after being treated with zoledronic acid and taxanes, plus corticosteroids.
A retrospective analysis of data registered in the archives of two Italian osteonecrosis of the jaws treatment centers, who are based at the University of Messina and at the University of Palermo, was performed in order to study, in these patients, demographic data and characteristics such as frequency of cancer location, lines of therapy, frequency of cancer drugs, presence/absence of oral trigger, number, location, and stage of jaw osteonecrosis.
It was found that the majority of patients developed advanced stages of osteonecrosis, frequently complicated with infection.
It was hypothesized that the concurrent administration of chemotherapeutic agents could be eventually considered as a factor able to allow a faster worsening of the clinical manifestation through the exacerbation of soft tissue defects, due to chemotherapy drugs.
American Psychological Association (APA)
Oteri, Giacomo& Campisi, G.& Panzarella, Vera& Morreale, Ilaria& Nucera, Riccardo& Di Fede, O.…[et al.]. 2018. Could the Combined Administration of Bone Antiresorptive Drug, Taxanes, and Corticosteroids Worsen Medication Related Osteonecrosis of the Jaws in Cancer Patients?. BioMed Research International،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1126281
Modern Language Association (MLA)
Oteri, Giacomo…[et al.]. Could the Combined Administration of Bone Antiresorptive Drug, Taxanes, and Corticosteroids Worsen Medication Related Osteonecrosis of the Jaws in Cancer Patients?. BioMed Research International No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1126281
American Medical Association (AMA)
Oteri, Giacomo& Campisi, G.& Panzarella, Vera& Morreale, Ilaria& Nucera, Riccardo& Di Fede, O.…[et al.]. Could the Combined Administration of Bone Antiresorptive Drug, Taxanes, and Corticosteroids Worsen Medication Related Osteonecrosis of the Jaws in Cancer Patients?. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1126281
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1126281