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Role of the CHADS2 Score in the Evaluation of Carotid Atherosclerosis in Patients with Atrial Fibrillation Undergoing Carotid Artery Ultrasonography
Joint Authors
Lin, Le-yu
Yang, Lian-wei
Shang, Yuan-yuan
Li, Yi-hui
Zhong, Ming
Zhang, Wei
Zhu, Hui
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-08-19
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Objective.
This study investigated the characteristics of carotid atherosclerosis in patients with atrial fibrillation (AF) and determined the feasibility and significance of the CHADS2 score in predicting the degree of carotid atherosclerosis.
Methods.
Consecutive patients (n = 109) with nonvalvular AF were registered and classified into two groups, the paroxysmal AF group (n = 59) and persistent AF group (n = 50).
Fifty healthy patients, matched by sex and age, were considered the control group.
All patients were examined using carotid ultrasound and velocity vector imaging (VVI).
Results.
Compared with the control group, the mean intimal-medial thickness in the paroxysmal AF group (0.56 ± 0.11 versus 0.61 ± 0.10, respectively, P < 0.05) and the persistent AF group (0.56 ± 0.11 versus 0.64 ± 0.13, respectively, P < 0.001) was significantly increased.
The plaque index (PI) in the persistent AF group was significantly higher than that observed in the paroxysmal AF group (1.05 ± 1.33 versus 1.42 ± 1.47, respectively, P < 0.001).
Regarding the VVI indices, those reflecting the long-axis longitudinal motion function of carotid arteries were significantly decreased in both AF groups.
Compared with the control group, a significantly lower total longitudinal displacement (tLoD) index was observed in the persistent AF group (0.73 ± 0.66 versus 0.31 ± 0.23, respectively, P < 0·0001) and the paroxysmal AF group (0.73 ± 0.66 versus 0.34 ± 0.17, P < 0·0001).
The CHADS2 score was related to indicators reflecting the structure and function of the carotid artery.
Conclusions.
Carotid arterial structure and function were significantly altered in patients with AF.
The degree of carotid atherosclerosis depended on the duration of AF.
The CHADS2 score may be useful as a predictor of the extent of carotid atherosclerosis in patients with AF.
American Psychological Association (APA)
Lin, Le-yu& Yang, Lian-wei& Shang, Yuan-yuan& Li, Yi-hui& Zhong, Ming& Zhang, Wei…[et al.]. 2018. Role of the CHADS2 Score in the Evaluation of Carotid Atherosclerosis in Patients with Atrial Fibrillation Undergoing Carotid Artery Ultrasonography. BioMed Research International،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1126347
Modern Language Association (MLA)
Lin, Le-yu…[et al.]. Role of the CHADS2 Score in the Evaluation of Carotid Atherosclerosis in Patients with Atrial Fibrillation Undergoing Carotid Artery Ultrasonography. BioMed Research International No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1126347
American Medical Association (AMA)
Lin, Le-yu& Yang, Lian-wei& Shang, Yuan-yuan& Li, Yi-hui& Zhong, Ming& Zhang, Wei…[et al.]. Role of the CHADS2 Score in the Evaluation of Carotid Atherosclerosis in Patients with Atrial Fibrillation Undergoing Carotid Artery Ultrasonography. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1126347
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1126347