Effects of Withania somnifera on Reproductive System: A Systematic Review of the Available Evidence
Joint Authors
Moini Jazani, Arezoo
Nazemiyeh, Hossein
Sadeghi Bazargani, Homayoun
Fazljou, Seyed Mohammad Bagher
Nasimi Doost Azgomi, Ramin
Zomorrodi, Afshar
Nejatbakhsh, Fatemeh
Ahmadi AsrBadr, Yadollah
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-17, 17 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-01-24
Country of Publication
Egypt
No. of Pages
17
Main Subjects
Abstract EN
Introduction.
Withania somnifera (WS) also known as ashwagandha is a well-known medicinal plant used in traditional medicine in many countries for infertility treatment.
The present study was aimed at systemically reviewing therapeutic effects of WS on the reproductive system.
Methods.
This systematic review study was designed in 2016.
Required data were obtained from PubMed, Scopus, Google Scholar, Cochrane Library, Science Direct, Web of Knowledge, Web of Science, and manual search of articles, grey literature, reference checking, and expert contact.
Results.
WS was found to improve reproductive system function by many ways.
WS extract decreased infertility among male subjects, due to the enhancement in semen quality which is proposed due to the enhanced enzymatic activity in seminal plasma and decreasing oxidative stress.
Also, WS extract improved luteinizing hormone and follicular stimulating hormone balance leading to folliculogenesis and increased gonadal weight, although some animal studies had concluded that WS had reversible spermicidal and infertilizing effects in male subjects.
Conclusion.
WS was found to enhance spermatogenesis and sperm related indices in male and sexual behaviors in female.
But, according to some available evidences for spermicidal features, further studies should focus on the extract preparation method and also dosage used in their study protocols.
American Psychological Association (APA)
Nasimi Doost Azgomi, Ramin& Zomorrodi, Afshar& Nazemiyeh, Hossein& Fazljou, Seyed Mohammad Bagher& Sadeghi Bazargani, Homayoun& Nejatbakhsh, Fatemeh…[et al.]. 2018. Effects of Withania somnifera on Reproductive System: A Systematic Review of the Available Evidence. BioMed Research International،Vol. 2018, no. 2018, pp.1-17.
https://search.emarefa.net/detail/BIM-1126350
Modern Language Association (MLA)
Nasimi Doost Azgomi, Ramin…[et al.]. Effects of Withania somnifera on Reproductive System: A Systematic Review of the Available Evidence. BioMed Research International No. 2018 (2018), pp.1-17.
https://search.emarefa.net/detail/BIM-1126350
American Medical Association (AMA)
Nasimi Doost Azgomi, Ramin& Zomorrodi, Afshar& Nazemiyeh, Hossein& Fazljou, Seyed Mohammad Bagher& Sadeghi Bazargani, Homayoun& Nejatbakhsh, Fatemeh…[et al.]. Effects of Withania somnifera on Reproductive System: A Systematic Review of the Available Evidence. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-17.
https://search.emarefa.net/detail/BIM-1126350
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1126350