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Polyphenols in Colorectal Cancer: Current State of Knowledge including Clinical Trials and Molecular Mechanism of Action
Joint Authors
Haq, Fazlul
Alam, Md Nur
Almoyad, Muhammad
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-29, 29 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-01-15
Country of Publication
Egypt
No. of Pages
29
Main Subjects
Abstract EN
Polyphenols have been reported to have wide spectrum of biological activities including major impact on initiation, promotion, and progression of cancer by modulating different signalling pathways.
Colorectal cancer is the second most major cause of mortality and morbidity among females and the third among males.
The objective of this review is to describe the activity of a variety of polyphenols in colorectal cancer in clinical trials, preclinical studies, and primary research.
The molecular mechanisms of major polyphenols related to their beneficial effects on colorectal cancer are also addressed.
Synthetic modifications and other future directions towards exploiting of natural polyphenols against colorectal cancer are discussed in the last section.
American Psychological Association (APA)
Alam, Md Nur& Almoyad, Muhammad& Haq, Fazlul. 2018. Polyphenols in Colorectal Cancer: Current State of Knowledge including Clinical Trials and Molecular Mechanism of Action. BioMed Research International،Vol. 2018, no. 2018, pp.1-29.
https://search.emarefa.net/detail/BIM-1126416
Modern Language Association (MLA)
Alam, Md Nur…[et al.]. Polyphenols in Colorectal Cancer: Current State of Knowledge including Clinical Trials and Molecular Mechanism of Action. BioMed Research International No. 2018 (2018), pp.1-29.
https://search.emarefa.net/detail/BIM-1126416
American Medical Association (AMA)
Alam, Md Nur& Almoyad, Muhammad& Haq, Fazlul. Polyphenols in Colorectal Cancer: Current State of Knowledge including Clinical Trials and Molecular Mechanism of Action. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-29.
https://search.emarefa.net/detail/BIM-1126416
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1126416