![](/images/graphics-bg.png)
The Essential Thrombocythemia, Thrombotic Risk Stratification, and Cardiovascular Risk Factors
Joint Authors
Russo, Antonio
Di Piazza, Florinda
Perez, Alessandro
Mancuso, Salvatrice
Accurso, Vincenzo
Santoro, Marco
Raso, Simona
Contrino, Angelo Davide
Siragusa, Sergio
Florena, Ada Maria
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-03-27
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Essential thrombocythemia is a rare hematological malignancy with good overall survival, but moderate to high risk of developing arterial or venous thrombosis lifelong.
Different thrombotic risk scores for patients with essential thrombocythemia have been proposed, but only one of them (the IPSET-t scoring system) takes into account the classical cardiovascular risk factors as one of the scoring items.
Currently, in clinical practice, the presence of cardiovascular risk factors in patients with diagnosis of ET rarely determines the decision to initiate cytoreductive therapies.
In our study, we compared different risk models to estimate the thrombotic risk of 233 ET patients and the role of specific driver mutations and evaluated the impact that conventional cardiovascular risk factors (hypertension, cigarette smoking, diabetes, obesity, and dyslipidaemia) have on thrombotic risk in patients with ET.
Perspective studies conducted on a polycentric large cohort of patients should be conducted to estimate the impact of cardiovascular risk factors in determining thrombosis in ET patients, evaluating the opportunity of initiating a cytoreductive therapy in patients with cardiovascular risk factors, even if classified into low to moderate risk groups according to other scoring systems.
American Psychological Association (APA)
Mancuso, Salvatrice& Accurso, Vincenzo& Santoro, Marco& Raso, Simona& Contrino, Angelo Davide& Perez, Alessandro…[et al.]. 2020. The Essential Thrombocythemia, Thrombotic Risk Stratification, and Cardiovascular Risk Factors. Advances in Hematology،Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1126449
Modern Language Association (MLA)
Mancuso, Salvatrice…[et al.]. The Essential Thrombocythemia, Thrombotic Risk Stratification, and Cardiovascular Risk Factors. Advances in Hematology No. 2020 (2020), pp.1-5.
https://search.emarefa.net/detail/BIM-1126449
American Medical Association (AMA)
Mancuso, Salvatrice& Accurso, Vincenzo& Santoro, Marco& Raso, Simona& Contrino, Angelo Davide& Perez, Alessandro…[et al.]. The Essential Thrombocythemia, Thrombotic Risk Stratification, and Cardiovascular Risk Factors. Advances in Hematology. 2020. Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1126449
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1126449