Stem Cells from the Apical Papilla: A Promising Source for Stem Cell-Based Therapy
Joint Authors
Kang, Jun
Fan, Wenguo
Deng, Qianyi
He, Hongwen
Huang, Fang
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-01-29
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Stem cells are biological cells that can self-renew and can differentiate into multiple cell lineages.
Stem cell-based therapy is emerging as a promising alternative therapeutic option for various disorders.
Mesenchymal stem cells (MSCs) are multipotent adult stem cells that are isolated from various tissues and can be used as an alternative to embryonic stem cells.
Stem cells from the apical papilla (SCAPs) are a novel population of MSCs residing in the apical papilla of immature permanent teeth.
SCAPs present the characteristics of expression of MSCs markers, self-renewal, proliferation, migration, differentiation, and immunosuppression, which support the application of SCAPs in stem cell-based therapy, including the immunotherapy and the regeneration of dental tissues, bone, neural, and vascular tissues.
In view of these properties and therapeutic potential, SCAPs can be considered as promising candidates for stem cell-based therapy.
Thus the aim of our review was to summarize the current knowledge of SCAPs considering isolation, characterization, and multilineage differentiation.
The prospects for their use in stem cell-based therapy were also discussed.
American Psychological Association (APA)
Kang, Jun& Fan, Wenguo& Deng, Qianyi& He, Hongwen& Huang, Fang. 2019. Stem Cells from the Apical Papilla: A Promising Source for Stem Cell-Based Therapy. BioMed Research International،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1126472
Modern Language Association (MLA)
Kang, Jun…[et al.]. Stem Cells from the Apical Papilla: A Promising Source for Stem Cell-Based Therapy. BioMed Research International No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1126472
American Medical Association (AMA)
Kang, Jun& Fan, Wenguo& Deng, Qianyi& He, Hongwen& Huang, Fang. Stem Cells from the Apical Papilla: A Promising Source for Stem Cell-Based Therapy. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1126472
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1126472