The Development and Lifetime Stability Improvement of Guanosine-Based Supramolecular Hydrogels through Optimized Structure

Joint Authors

Chen, Miao
Lin, Weimin
Hong, Le
Ji, Ning
Zhao, Hang

Source

BioMed Research International

Issue

Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-18, 18 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2019-06-13

Country of Publication

Egypt

No. of Pages

18

Main Subjects

Medicine

Abstract EN

Guanosine is an important building block for supramolecular gels owing to the unique self-assembly property that results from the unique hydrogen bond acceptors and donor groups.

Guanosine-derived supramolecular hydrogels have promise in the fields of drug delivery, targeted release, tissue engineering applications, etc.

However, the property of poor longevity and the need for excess cations hinder the widespread applications of guanosine hydrogels.

Although guanosine-derived supramolecular hydrogels have been reviewed previously by Dash et al., the structural framework of this review is different, as the modification of guanosine is described at the molecular level.

In this review, we summarize the development and lifetime stability improvement of guanosine-based supramolecular hydrogels through optimized structure and elaborate on three aspects: sugar modification, base modification, and binary gels.

Additionally, we introduce the concept and recent research progress of self-healing gels, providing inspiration for the development of guanosine-derived supramolecular hydrogels with longer lifespans, unique physicochemical properties, and biological activities.

American Psychological Association (APA)

Chen, Miao& Lin, Weimin& Hong, Le& Ji, Ning& Zhao, Hang. 2019. The Development and Lifetime Stability Improvement of Guanosine-Based Supramolecular Hydrogels through Optimized Structure. BioMed Research International،Vol. 2019, no. 2019, pp.1-18.
https://search.emarefa.net/detail/BIM-1126569

Modern Language Association (MLA)

Chen, Miao…[et al.]. The Development and Lifetime Stability Improvement of Guanosine-Based Supramolecular Hydrogels through Optimized Structure. BioMed Research International No. 2019 (2019), pp.1-18.
https://search.emarefa.net/detail/BIM-1126569

American Medical Association (AMA)

Chen, Miao& Lin, Weimin& Hong, Le& Ji, Ning& Zhao, Hang. The Development and Lifetime Stability Improvement of Guanosine-Based Supramolecular Hydrogels through Optimized Structure. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-18.
https://search.emarefa.net/detail/BIM-1126569

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1126569