The Development and Lifetime Stability Improvement of Guanosine-Based Supramolecular Hydrogels through Optimized Structure
Joint Authors
Chen, Miao
Lin, Weimin
Hong, Le
Ji, Ning
Zhao, Hang
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-18, 18 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-06-13
Country of Publication
Egypt
No. of Pages
18
Main Subjects
Abstract EN
Guanosine is an important building block for supramolecular gels owing to the unique self-assembly property that results from the unique hydrogen bond acceptors and donor groups.
Guanosine-derived supramolecular hydrogels have promise in the fields of drug delivery, targeted release, tissue engineering applications, etc.
However, the property of poor longevity and the need for excess cations hinder the widespread applications of guanosine hydrogels.
Although guanosine-derived supramolecular hydrogels have been reviewed previously by Dash et al., the structural framework of this review is different, as the modification of guanosine is described at the molecular level.
In this review, we summarize the development and lifetime stability improvement of guanosine-based supramolecular hydrogels through optimized structure and elaborate on three aspects: sugar modification, base modification, and binary gels.
Additionally, we introduce the concept and recent research progress of self-healing gels, providing inspiration for the development of guanosine-derived supramolecular hydrogels with longer lifespans, unique physicochemical properties, and biological activities.
American Psychological Association (APA)
Chen, Miao& Lin, Weimin& Hong, Le& Ji, Ning& Zhao, Hang. 2019. The Development and Lifetime Stability Improvement of Guanosine-Based Supramolecular Hydrogels through Optimized Structure. BioMed Research International،Vol. 2019, no. 2019, pp.1-18.
https://search.emarefa.net/detail/BIM-1126569
Modern Language Association (MLA)
Chen, Miao…[et al.]. The Development and Lifetime Stability Improvement of Guanosine-Based Supramolecular Hydrogels through Optimized Structure. BioMed Research International No. 2019 (2019), pp.1-18.
https://search.emarefa.net/detail/BIM-1126569
American Medical Association (AMA)
Chen, Miao& Lin, Weimin& Hong, Le& Ji, Ning& Zhao, Hang. The Development and Lifetime Stability Improvement of Guanosine-Based Supramolecular Hydrogels through Optimized Structure. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-18.
https://search.emarefa.net/detail/BIM-1126569
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1126569