Right Ventricle Remodeling and Function in Scleroderma Patients
Joint Authors
Cucuruzac, Roxana
Muntean, Iolanda
Benedek, Imre
Mester, Andras
Rat, Nora
Mitre, Adriana
Chitu, Monica
Benedek, Theodora
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-03-20
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Scleroderma, known also as systemic sclerosis (SSc), is a severe disease associated with high mortality rates, and right ventricular (RV) remodeling and dysfunction, along with pulmonary artery hypertension (PAH), are among the most important internal organ manifestations of this disease.
PAH has a higher prevalence in patients with SSc compared to the general population and represents a significant predictor of mortality in SSc.
In patients with SSc, the morphological remodeling and alteration of RV function begin even before the setting of PAH and lead to development of a specific adaptive pattern of the RV which is different from the one recorded in patients with IAPH.
These alterations cause worse outcomes and increased mortality rates in SSc patients.
Early detection of RV dysfunction and remodeling is possible using modern imaging tools currently available and can indicate the initiation of specific therapeutic measures before installation of PAH.
The aim of this review is to summarize the current knowledge related to mechanisms involved in the remodeling and functional alteration of the RV in SSc patients.
American Psychological Association (APA)
Cucuruzac, Roxana& Muntean, Iolanda& Benedek, Imre& Mester, Andras& Rat, Nora& Mitre, Adriana…[et al.]. 2018. Right Ventricle Remodeling and Function in Scleroderma Patients. BioMed Research International،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1126715
Modern Language Association (MLA)
Cucuruzac, Roxana…[et al.]. Right Ventricle Remodeling and Function in Scleroderma Patients. BioMed Research International No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1126715
American Medical Association (AMA)
Cucuruzac, Roxana& Muntean, Iolanda& Benedek, Imre& Mester, Andras& Rat, Nora& Mitre, Adriana…[et al.]. Right Ventricle Remodeling and Function in Scleroderma Patients. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1126715
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1126715